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- 抗原 See all Syntaxin 4 (STX4) 抗体
- Syntaxin 4 (STX4)
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抗原表位
- AA 2-23, Intracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Syntaxin 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
- 原理
- A Rabbit Polyclonal Antibody to Syntaxin 4
- 特异性
- Intracellular, N-terminus
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Mouse - identical, human - 17,22 amino acid residues identical
- 产品特性
- Anti-Syntaxin 4 Antibody is directed against an epitope of rat Syntaxin 4. Anti-Syntaxin 4 Antibody (ABIN7043796, ABIN7044650 and ABIN7044651)) can be used in western blot and immunohistochemical applications. It was designed to recognize Syntaxin 4 from rat, mouse and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: RDRTHELRQGDNISDDEDEVRV(C), corresponding to residues 2-23 of rat syntaxin 4
- 亚型
- IgG
- Top Product
- Discover our top product STX4 Primary Antibody
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anti-Syntaxin 4 (STX4) (AA 19-119) antibody
STX4 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6A1 unconjugated
anti-Syntaxin 4 (STX4) (AA 1-297) antibodySTX4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) antibodySTX4 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Syntaxin 4 (STX4) (AA 1-297) antibodySTX4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) (AA 101-150) antibodySTX4 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) (C-Term) antibodySTX4 适用: 人, Cow, Pig, 兔, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) (AA 1-273), (Cytoplasmic Domain) antibodySTX4 适用: 人, 小鼠, 大鼠, Hamster WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) (AA 1-273), (Cytoplasmic Domain) antibodySTX4 适用: 小鼠, 大鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal 139-2 unconjugated
anti-Syntaxin 4 (STX4) (AA 1-275) antibodySTX4 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) antibodySTX4 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 4E1 unconjugated Recombinant Antibody
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:400
- 说明
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Negative Control: BLP-NR004
Blocking Peptide: BLP-NR004
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Syntaxin 4 (STX4)
- 别名
- STX4 (STX4 产品)
- 背景
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STX4, Renal carcinoma antigen NY-REN-31, P35-2,Syntaxin 4 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionarily conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2.SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.Syntaxin 4, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.Syntaxin 4 functions as a plasma membrane protein t-SNARE and has been shown to have an important role in pancreatic b-cell insulin secretion and in insulin-stimulated glucose uptake in skeletal muscle and adipose tissue by means of translocation of the glucose transporter GLUT4 from an intracellular compartment to the plasma membrane3,4.
Alternative names: Syntaxin 4, STX4, Renal carcinoma antigen NY-REN-31, P35-2 - 基因ID
- 81803
- NCBI登录号
- NM_004604
- UniProt
- Q08850
- 途径
- Synaptic Vesicle Exocytosis
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