STX2 抗体 (N-Term)
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Quick Overview for STX2 抗体 (N-Term) (ABIN7043794)
抗原
See all STX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-19, N-Term
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原理
- A Rabbit Polyclonal Antibody to Syntaxin 2
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预测反应
- Human - 16,17 amino acid residues identical, mouse - 15
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产品特性
- Anti-Syntaxin 2 Antibody is directed against an epitope of rat Syntaxin 2. Anti-Syntaxin 2 Antibody (ABIN7043794 and ABIN7044655) can be used in western blot and immunohistochemistry applications. It has been designed to recognize Syntaxin 2 from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- RDRLPDLTACRKSDDGDN, corresponding to amino acid residues 2-19 of rat Syntaxin 2
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亚型
- IgG
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anti-Syntaxin 2 (STX2) (AA 8-262) antibody
STX2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 2 (STX2) (AA 1-287) antibodySTX2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 2 (STX2) antibodySTX2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 2 (STX2) (AA 123-152) antibodySTX2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12390 unconjugated
anti-Syntaxin 2 (STX2) (AA 1-19) antibodySTX2 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig, 犬, 猴, Hamster, Drosophila melanogaster, 小鸡, 绵羊, 非洲爪蟾 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 2 (STX2) (AA 1-19) antibodySTX2 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig, 猴, Hamster, Drosophila melanogaster, 小鸡, 绵羊, 非洲爪蟾, Insect WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 2 (STX2) (AA 1-287) antibodySTX2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Syntaxin 2 (STX2) (AA 122-152), (Middle Region) antibodySTX2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 2 (STX2) (AA 1-264) antibodySTX2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 2 (STX2) (AA 68-117) antibodySTX2 适用: 人, 小鼠, 大鼠, 兔, Pig, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:600
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7566009)
Blocking Peptide: (ABIN7566009)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- STX2 (Syntaxin 2 (STX2))
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别名
- STX2
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背景
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Synonyms: STX2, Epimorphin, EPIM
Description: Syntaxin 2 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionarily conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2.SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.Syntaxin 2, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.Syntaxin 2 functions as a plasma membrane protein t-SNARE, which together with vesicular v-SNARE proteins is involved in regulated exocytosis in cells such as platelets, sperm cells and pancreatic acinar cells3-5. Intriguingly, Syntaxin 2 has been also identified as epimorphin, an extracellular membrane protein implicated in branching morphogenesis, a developmental process essential for the formation of many organs, including mammary gland, lung, kidney, and salivary gland6.
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基因ID
- 25130
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NCBI登录号
- NM_194356
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UniProt
- P50279
抗原
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