Synapsin III 抗体 (C-Term, Extracellular)
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Quick Overview for Synapsin III 抗体 (C-Term, Extracellular) (ABIN7043788)
抗原
See all Synapsin III (SYN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 510-523, C-Term, Extracellular
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原理
- A Rabbit Polyclonal Antibody to Synapsin III
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,human - identical
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产品特性
- Anti-Synapsin III (SYN3) Antibody (ABIN7043788, ABIN7044664 and ABIN7044665) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize Synapsin III from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)RPPVQGRSTSQQGE, corresponding to amino acid residues 510-523 of rat Synapsin III
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亚型
- IgG
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应用备注
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WB: 1:200-1:400
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7237315)
Blocking Peptide: (ABIN7237315)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Synapsin III (SYN3)
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别名
- SYN3
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背景
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Synonyms: Synapsin-3
Description: Synapsin 3 (Syn3) belongs to the synapsin family of neuronal phosphoproteins, vesicle-associated proteins that includes two additional members: Synapsin I and Synapsin II. Alternative splicing of the genes results in at least ten variants with various levels of homology.Synapsins are involved in synaptogenesis, synaptic transmission and synaptic plasticity and are required for the formation and maintenance of the reserve and recycling pools of synaptic vesicles through association with the actin cytoskeleton. Several protein kinases, including PKA, calcium-calmodulin regulated protein kinases and the mitogen-activated protein kinase (MAPK) use synapsins as their substrates1-4.Syn3 plays an important role in several disorders, including bipolar disorder, schizophrenia and epilepsy1.
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基因ID
- 29130
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NCBI登录号
- NM_001135774
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UniProt
- O70441
抗原
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