Stim2 抗体 (Intracellular)
Quick Overview for Stim2 抗体 (Intracellular) (ABIN7043782)
抗原
See all Stim2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 583-597, Intracellular
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原理
- A Rabbit Polyclonal Antibody to STIM2
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特异性
- Intracellular, C-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,mouse,bovine - identical
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产品特性
- Anti-STIM2 Antibody (ABIN7043782, ABIN7044028 and ABIN7044029) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize STIM2 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: SAEKQWEVPDTASEC, corresponding to amino acid residues 583-597 of human STIM2
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亚型
- IgG
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anti-Stromal Interaction Molecule 2 (Stim2) (AA 60-180) antibody
Stim2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 471-656) antibodyStim2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 98-127) antibodyStim2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 663-712) antibodyStim2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 98-127), (N-Term) antibodyStim2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19223 unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (C-Term) antibodyStim2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 2 (Stim2) (AA 97-127), (N-Term) antibodyStim2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IP|ICC
Negative Control: (ABIN7237296)
Blocking Peptide: (ABIN7237296)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Stim2 (Stromal Interaction Molecule 2 (Stim2))
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别名
- STIM2
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背景
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Stromal interaction molecule 2,Cytosolic Ca2+ has long been known to act as a key second messenger in many intracellular pathways including synaptic transmission, muscle contraction, hormonal secretion, cell growth and proliferation.1,2 The mechanism controlling the influx of intracellular Ca2+ either by calcium-release-activated Ca2+ channels (CRAC) or from intracellular stores has lately become the focus of intense research.Recently, several key players of the store-operated complex have been identified: the Orai family consists of three members: Orai1-3, and the STIM family, which consists of two members, STIM1 and STIM2.3 Orai1 (also known as CRACM1) acts as the store-operated calcium channel (SOC) and STIM1 as the endoplasmic reticulum (ER) Ca2+ sensor.3,4While STIM1 appears to be localized intracellularly at the ER membrane and at a much lower extent on the cell surface of several cell types, STIM2 appears to be localized solely at the ER membrane.5 The function of STIM2 still remains elusive and several models have been suggested.6-8
Alternative names: STIM2, Stromal interaction molecule 2 -
基因ID
- 57620
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NCBI登录号
- NM_020860
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UniProt
- Q9P246
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途径
- TCR Signaling, BCR Signaling
抗原
-
