S1PR5 抗体 (Extracellular)
Quick Overview for S1PR5 抗体 (Extracellular) (ABIN7043777)
抗原
See all S1PR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-39, Extracellular
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原理
- A Rabbit Polyclonal Antibody to Sphingosine 1-Phosphate Receptor 5
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特异性
- Extracellular, N-terminus
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交叉反应
- 小鼠, 大鼠
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预测反应
- Rat,human - identical
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产品特性
- Anti-S1PR5/EDG8 (extracellular) Antibody (ABIN7043777, ABIN7045276 and ABIN7045277) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot analysis. It has been designed to recognize EDG8 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KLRGARYQPGAGLRAD, corresponding to amino acid residues 24-39 of mouse S1PR5 (EDG8)
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亚型
- IgG
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anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 1-200) antibody
S1PR5 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 1-50) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, Opossum WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 309-398) antibodyS1PR5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 大鼠, Pig, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (C-Term) antibodyS1PR5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Drosophila melanogaster, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) antibodyS1PR5 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7237280)
Blocking Peptide: (ABIN7237280)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
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别名
- S1PR5
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背景
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S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Lysophospholipid receptor B4, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8,Sphingosine-1-phosphate receptor 5 also known as S1PR5 (EDG8) is a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).Lysophospholipids encompass a broad range of small, membrane-derived phospholipids that act as extracellular signals, mediated through specific receptors1. S1PR5 is a high-affinity cell surface S1P receptor, a member of the S1PR family. Like all GPCRs it has the classical structure of seven transmembrane domains, an extracellular N-terminus and a cytosolic C-terminal1.The signaling pathways triggered by S1P/S1P binding play a critical regulatory role in many pathophysiological processes, including skeletal muscle and nervous system degeneration, inflammation, cancer, and autoimmune disorders and hence this interaction has important implications for clinical applications and for personalized medicine2,3. Targeting S1P receptors and their downstream signaling cascades is considered as a potential treatment for cancer and various autoimmune diseases4.
Alternative names: S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Lysophospholipid receptor B4, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8 -
基因ID
- 94226
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NCBI登录号
- NM_030760
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UniProt
- Q91X56
抗原
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