S1PR2 抗体 (AA 129-146)
Quick Overview for S1PR2 抗体 (AA 129-146) (ABIN7043773)
抗原
See all S1PR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 129-146
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原理
- A Rabbit Polyclonal Antibody to Sphingosine 1-Phosphate Receptor 2
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特异性
- 2nd intracellular loop
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat - 17,18 amino acid residues identical, human - 16
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产品特性
- Anti-S1PR2 (EDG5) Antibody is directed against an intracellular epitope of mouse sphingosine 1-phosphate receptor 2. Anti-S1PR2 (EDG5) Antibody (ABIN7043773, ABIN7045272 and ABIN7045273) can be used in western blot and immunohistochemistry applications. It has been designed to recognize S1PR2 from mouse, rat and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: ERQVALAKVKLYGSDKSC, corresponding to amino acid residues 129-146 of mouse S1PR2
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亚型
- IgG
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anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (AA 293-353) antibody
S1PR2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (C-Term) antibodyS1PR2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (Internal Region) antibodyS1PR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (AA 39-73) antibodyS1PR2 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB53162 unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (Internal Region) antibodyVerified S1PR2 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (AA 272-298) antibodyS1PR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) antibodyS1PR2 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IHC
Negative Control: (ABIN7237271)
Blocking Peptide: (ABIN7237271)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))
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别名
- S1PR2
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背景
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Sphingosine 1-phosphate receptor 2, S1P2, Endothelial differentiation G-protein coupled receptor 5, Lysophospholipid receptor B2, LPB2,Lysophospholipids constitute a group of important lipid mediators, lysophosphatidic acid (LPA) a glycerolysophospholipid and sphingosine 1-phosphate (S1P), a lysosphingolipid. Sphingosine 1-phosphate is a bioactive lipid derived from metabolism of sphingomyelin1. Sphingosine 1-phosphate is implicated in the regulation of many cellular functions including proliferation, apoptosis, survival, adhesion, differentiation, and migration2.Sphingosine 1-phosphate exerts its activity through five distinct G-protein-coupled receptors, (also named endothelial differentiation gene receptors - EDG), S1PR1 (EDG-1), S1PR2 (EDG-5), S1PR3 (EDG-3), S1PR4 (EDG-6), and S1PR5 (EDG-8)3.Sphingosine 1-phosphate receptor 2 (S1PR2) is ubiquitously expressed. S1PR2 mRNA was detected in the brain, heart, spleen, liver, lung, thymus, kidney and skeletal muscle4. Unlike S1PR1, knockout of SIPR2 gene is not lethal5.
Alternative names: S1PR2 (EDG5), Sphingosine 1-phosphate receptor 2, S1P2, Endothelial differentiation G-protein coupled receptor 5, Lysophospholipid receptor B2, LPB2 -
基因ID
- 14739
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NCBI登录号
- NM_004230
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UniProt
- P52592
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途径
- Synaptic Membrane
抗原
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