SSTR1 抗体 (Extracellular)
Quick Overview for SSTR1 抗体 (Extracellular) (ABIN7043763)
抗原
See all SSTR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 26-40, Extracellular
-
原理
- A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 1
-
特异性
- Extracellular, N-terminus
-
交叉反应
- 小鼠, 大鼠
-
预测反应
- Mouse - identical, human - 13,15 amino acid residues identical
-
产品特性
- Anti-Somatostatin Receptor Type 1 (extracellular) Antibody (ABIN7043763 and ABIN7045262) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize SSTR1 from rat, mouse, and human samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: CSRGPGSGAADGMEE, corresponding to amino acid residues 26-40 of rat SSTR1
-
亚型
- IgG
-
-
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:1000
Application Dilutions Western blot wb: 1:200
-
说明
-
Negative Control: (ABIN7237232)
Blocking Peptide: (ABIN7237232)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- SSTR1 (Somatostatin Receptor 1 (SSTR1))
-
别名
- SSTR1
-
背景
-
SSTR1, SS1R, SRIF-2, SRIF2A,Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both a stimulatory and inhibitory manner.1,2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.2Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.4
Alternative names: Somatostatin Receptor Type 1, SSTR1, SS1R, SRIF-2, SRIF2A -
基因ID
- 25033
-
NCBI登录号
- NM_001049
-
UniProt
- P28646
抗原
-