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SSTR1 抗体 (Extracellular)

This anti-SSTR1 antibody is a 兔 多克隆 antibody detecting SSTR1 in WB 和 IHC. Suitable for 大鼠.
产品编号 ABIN7043763
发货至: 中国

Quick Overview for SSTR1 抗体 (Extracellular) (ABIN7043763)

抗原

See all SSTR1 抗体
SSTR1 (Somatostatin Receptor 1 (SSTR1))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This SSTR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    AA 26-40, Extracellular

    原理

    A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 1

    特异性

    Extracellular, N-terminus

    交叉反应

    小鼠, 大鼠

    预测反应

    Mouse - identical, human - 13,15 amino acid residues identical

    产品特性

    Anti-Somatostatin Receptor Type 1 (extracellular) Antibody (ABIN7043763 and ABIN7045262) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize SSTR1 from rat, mouse, and human samples.

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: CSRGPGSGAADGMEE, corresponding to amino acid residues 26-40 of rat SSTR1

    亚型

    IgG
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:1000

    Application Dilutions Western blot wb: 1:200

    说明

    Negative Control: (ABIN7237232)

    Blocking Peptide: (ABIN7237232)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存条件

    4 °C,-20 °C

    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原

    SSTR1 (Somatostatin Receptor 1 (SSTR1))

    别名

    SSTR1

    背景

    SSTR1, SS1R, SRIF-2, SRIF2A,Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both a stimulatory and inhibitory manner.1,2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.2Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.4

    Alternative names: Somatostatin Receptor Type 1, SSTR1, SS1R, SRIF-2, SRIF2A

    基因ID

    25033

    NCBI登录号

    NM_001049

    UniProt

    P28646
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