SLC38A1 抗体 (Cytosolic, N-Term)
Our Local Distributor
北京 101111
Quick Overview for SLC38A1 抗体 (Cytosolic, N-Term) (ABIN7043722)
抗原
See all SLC38A1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 41-57, Cytosolic, N-Term
-
原理
- A Rabbit Polyclonal Antibody to SLC38A1 Transporter
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Mouse,human - identical
-
产品特性
- Anti-SLC38A1 Antibody (ABIN7043722, ABIN7044857 and ABIN7044858) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize SNAT1 from human, rat, and mouse samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- (C)SKFISDRESRRSLTNSH, corresponding to amino acid residues 41-57 of rat SLC38A1
-
亚型
- IgG
-
-
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (PerCP)
SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 PerCP
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (PE)SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 PE
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (Biotin)SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 Biotin
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (FITC)SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 FITC
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (HRP)SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 HRP
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (Atto 390)SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 Atto 390
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (Atto 488)SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 Atto 488
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (Atto 594)SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 Atto 594
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibody (APC)SLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 APC
anti-Solute Carrier Family 38 Member 1 (SLC38A1) (AA 1-63) antibodySLC38A1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S104-32 unconjugated
-
-
应用备注
-
WB: 1:200-1:500
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
-
说明
-
Negative Control: (ABIN7237083)
Blocking Peptide: (ABIN7237083)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
-
浓度
- 0.8 mg/mL
-
缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- SLC38A1 (Solute Carrier Family 38 Member 1 (SLC38A1))
-
别名
- SLC38A1
-
背景
-
Synonyms: Sodium-coupled neutral amino acid transporter 1, Snat1, Amino acid transporter A1, rATA1, Glutamine transporter, N-system amino acid transporter 2, Ata1, Glnt, Sa2, Sat1
Description: SNAT1 (SLC38A1, Sodium-coupled neutral amino acid transporter 1) is a 486 amino acids system A type sodium symporter that catalyzes the electrogenic Na+-dependent uptake of glutamine, among other substrates. SNAT1 is thought to be responsible for glutamine uptake into neurons1.SNAT1 belongs to the β-family of solute carriers that includes three SLC families, SLC32, SLC36, and SLC38. SNAT1 is a member of the SLC38 family that includes 11 members, SNAT1 to SNAT11.SNAT1 and SNAT2 are expressed in neurons and in glial cells all over the central nervous system, with high expression in perivascular glial profiles and lower expression in astrocytes of the cerebral parenchyma. This supports a role in controlling the amino acid permeability at the blood-brain barrier2. SNAT1 also acts as a positive regulator of mTORC1 signaling pathway in neurons and plays an important pathological role in the mechanism underlying neuronal survival after ischemia3. It was also shown to be up-regulated in specific types of cancer4.The structure of SNAT proteins is predicted to have a 5+5 inverted repeat fold typical of the bacterial LeuT, with intracellular N-terminus and extracellular and C-terminal tail5.
-
基因ID
- 170567
-
NCBI登录号
- NM_001077484
-
UniProt
- Q9JM15
抗原
-
