SLC3A1 抗体 (Extracellular)
Quick Overview for SLC3A1 抗体 (Extracellular) (ABIN7043713)
抗原
See all SLC3A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 277-291, Extracellular
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原理
- A Rabbit Polyclonal Antibody to SLC3A1
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特异性
- Extracellular, C-terminus
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交叉反应
- 小鼠, 大鼠
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预测反应
- Mouse - identical, human - 14,15 amino acid residues identical
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产品特性
- Anti-SLC3A1 (extracellular) Antibody (ABIN7043713, ABIN7044829 and ABIN7044830) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. The antibody recognizes an extracellular epitope and can potentially be used for detecting the protein in living cells. It has been designed to recognize SLC3A1 from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KEQPDLNFRNPAVQE, corresponding to amino acid residues 277-291 of rat SLC3A1
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亚型
- IgG
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anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 58-278) antibody
SLC3A1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 1-68) antibodySLC3A1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 211-320) antibodySLC3A1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 416-685) antibodySLC3A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 328-507) antibodySLC3A1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 211-320) antibodySLC3A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (C-Term) antibodySLC3A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 211-320) antibodySLC3A1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 1-685) antibodySLC3A1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Solute Carrier Family 3 Member 1 (SLC3A1) (AA 179-228) antibodySLC3A1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔, 斑马鱼, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:400
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说明
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Negative Control: (ABIN7237055)
Blocking Peptide: (ABIN7237055)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- SLC3A1 (Solute Carrier Family 3 Member 1 (SLC3A1))
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别名
- SLC3A1
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背景
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Neutral and basic amino acid transport protein rBAT, Solute carrier family 3 (cystine, dibasic and neutral amino acid transporters) member 1, B(0,+)-type amino acid transport protein, NBAT, Amino acid transporter 1, ATR1,The heteromeric amino acid transporter (HAT) family is one of the major amino acid transporter families responsible for cellular uptake and epithelial transport. The uptake of cysteine mainly depends on HATs. HATs are localized to the plasma membrane and form heterodimers composed of a 12-membrane spanning light chain (SLC7) and a single membrane spanning heavy chain, SLC3. SLC7 catalyzes transport functions while SLC3 is essential for plasma membrane localization and stabilization of the light chains. The SLC3A1 is mainly expressed in the apical plasma membrane in the epithelial cells of intestinal mucosa and the renal proximal tubules1,2. Two heavy chains, SLC3A1 and SLC3A2 are covalently bound to the light chains through a disulfide bridge. SLC3A1 has been known to form a heterodimer only with SLC7A9, a family member of light chain1,2.Type 1 Cystinuria is associated with mutations in SLC3A1, an inherited disease characterized by the formation of cystine calculi in the kidneys, ureters, and bladder3.
Alternative names: SLC3A1, Neutral and basic amino acid transport protein rBAT, Solute carrier family 3 (cystine, dibasic and neutral amino acid transporters) member 1, B(0,+)-type amino acid transport protein, NBAT, Amino acid transporter 1, ATR1 -
基因ID
- 29484
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NCBI登录号
- NM_000341
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UniProt
- Q64319
抗原
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