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- 抗原 See all SLC29A3 抗体
- SLC29A3 (Solute Carrier Family 29 Member 3 (SLC29A3))
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抗原表位
- AA 37-49, Intracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC29A3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- A Rabbit Polyclonal Antibody to Equilibrative Nucleoside Transporter 3 (SLC29A3)
- 特异性
- Intracellular, N-terminus
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Mouse - identical, human - 10,13 amino acid residues identical
- 产品特性
- Anti-ENT3 (SLC29A3) Antibody (ABIN7043712, ABIN7044802 and ABIN7044803) is a highly specific antibody directed against an epitope of the rat equilibrative nucleoside transporter 3. The antibody can be used in western blot analysis. It has been designed to recognize ENT3 from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)DYPAPGLQRPEDR, corresponding to amino acid residues 37-49 of rat ENT3
- 亚型
- IgG
- Top Product
- Discover our top product SLC29A3 Primary Antibody
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anti-Solute Carrier Family 29 Member 3 (SLC29A3) (AA 1-110) antibody
SLC29A3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 29 Member 3 (SLC29A3) (AA 21-50), (N-Term) antibodySLC29A3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32652 unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7237052)
Blocking Peptide: (ABIN7237052)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- SLC29A3 (Solute Carrier Family 29 Member 3 (SLC29A3))
- 别名
- SLC29A3 (SLC29A3 产品)
- 背景
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Equilibrative nucleoside transporter 3,Equilibrative nucleoside transporter 3 (ENT3) is responsible for transporting nucleotide synthesis precursors, such as hydrophilic nucleosides and nucleobases within cells1. ENT3 structure includes 11 transmembrane domains and a 51-residue hydrophilic N-terminal region containing two dileucine motifs that are characteristic of endosomal/lysosomal targeting sequences1,2.ENT3 is encoded by the SLC29A3 gene and is expressed in several mouse and human tissues such as placenta, heart, neurons, and astrocytes. In addition, human ENT3 is predominantly expressed in mitochondria in human hepatocytes. Human ENTs are high-capacity transporters, bidirectional, Na+-independent with a wide substrate selectivity1,2. The human ENT family consists of four members: ENT1- ENT4. Nucleoside transport function of ENT3 is maximal at pH 5.5 suggesting that the protein is localized to acidic intracellular compartments, probably lysosomes1,2.Studies show that mutations in human ENT3 can cause various clinical disorders including H syndrome, pigmented hypertrichosis with insulin-dependent diabetes mellitus syndrome, lysosomal storage-like disorders and mitochondrial disorders1,2.
Alternative names: ENT3 (SLC29A3), Equilibrative nucleoside transporter 3 - 基因ID
- 353307
- NCBI登录号
- NM_018344
- UniProt
- Q80WK7
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