SLC28A3 抗体 (Extracellular)
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Quick Overview for SLC28A3 抗体 (Extracellular) (ABIN7043709)
抗原
See all SLC28A3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 432-447, Extracellular
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原理
- A Rabbit Polyclonal Antibody to SLC28A3/CNT3
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特异性
- 5th extracellular loop
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- human - 14,16 amino acid residues identical,Mouse - 15
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产品特性
- Anti-SLC28A3/CNT3 (extracellular) Antibody (ABIN7043709, ABIN7044807 and ABIN7044808) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and indirect live cell flow cytometry. It has been designed to recognize CNT3 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: Peptide (C)KITLKNAMKMENGDSR, corresponding to amino acid residues 432 - 447 of rat SLC28A3/CNT3
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亚型
- IgG
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anti-Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 3 (SLC28A3) (AA 1-102) antibody
SLC28A3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 3 (SLC28A3) (AA 612-691) antibodySLC28A3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 3 (SLC28A3) antibodySLC28A3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:400-1:500
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说明
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Negative Control: (ABIN7237037)
Blocking Peptide: (ABIN7237037)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- SLC28A3 (Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 3 (SLC28A3))
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别名
- SLC28A3
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背景
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Solute Carrier Family 28 Member 3, Concentrative Na+-Nucleoside Cotransporter 3,Solute carrier family 28 member 3 (SLC28A3, CNT3) is a sodium-dependent, concentrative pyrimidine- and purine-selective transporter. SLC28A3 plays an important role in mediating the cellular entry of a broad array of physiological nucleosides and synthetic anticancer nucleoside analog drugs, in a process that is coupled to the sodium cellular gradient1.CNT3 consists of 13 putative trans-membrane domains and it forms a homo-trimer which is important for its activity as a transporter2,3.SLC28 members are crucial determinants in the response to a variety of anticancer and antiviral nucleoside analogs, as they modulate the entry of these analogs into target tissues. Within this large group of solute carriers, SLC28A is a sub-group which consists of SLC28A1, SLC28A2, and SLC28A3. Of the three members of this sub-family, SLC28A3 has the broadest selectivity and the widest expression profile4.
Alternative names: Solute Carrier Family 28 Member 3, Concentrative Na+-Nucleoside Cotransporter 3, CNT3 -
基因ID
- 140944
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NCBI登录号
- NM_022127
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UniProt
- Q8VIH3
抗原
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