SLC22A4 抗体 (Intracellular)
Quick Overview for SLC22A4 抗体 (Intracellular) (ABIN7043704)
抗原
See all SLC22A4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 522-536, Intracellular
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原理
- A Rabbit Polyclonal antibody to OCTN1/SLC22A4 transporter.
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特异性
- Intracellular, C-terminus.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,rat - 14 out of 15 amino acid residues identical, Human - 12 out of 15 amino acid residues identical
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产品特性
- Anti-OCTN1/SLC22A4 Antibody (ABIN7043704, ABIN7044225 and ABIN7044226) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize OCTN1 from mouse, rat and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)EQMQKVRGFR(S)GKKS, corresponding to amino acid residues 522 - 536 of mouse OCTN1
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亚型
- IgG
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anti-Solute Carrier Family 22 Member 4 (SLC22A4) (AA 42-141) antibody
SLC22A4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 4 (SLC22A4) (AA 43-141) antibodySLC22A4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 4 (SLC22A4) (AA 514-542) antibodySLC22A4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 4 (SLC22A4) (AA 43-141) antibodySLC22A4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-Solute Carrier Family 22 Member 4 (SLC22A4) (C-Term) antibodySLC22A4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 4 (SLC22A4) (AA 42-141) antibodySLC22A4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:1200
Application Dilutions Western blot wb: 1:200-1:600
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说明
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Cited Application: IHC
Negative Control: (ABIN7237017)
Blocking Peptide: (ABIN7237017)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- SLC22A4 (Solute Carrier Family 22 Member 4 (SLC22A4))
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别名
- SLC22A4
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背景
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Organic Cation/Carnitine Transporter 1, Ergothioneine Transporter, Solute Carrier Family 22 Member 4,Organic Cation Transporter Novel (OCTN) is a subfamily of the larger Organic Cation Transporter (OCT) or SLC22 transporter family.The OCTN subfamily consists of two members in humans: OCTN1 (SLC22A4) and OCTN2 (SLC22A5) with a third member (SLC22A21) present only in rodents 1-2.The physiological role of OCTN1 (SLC22A4) has not yet been elucidated. OCTN1 is ubiquitously expressed throughout the body and transports various therapeutic agents, including organic cations and zwitterions. Ergothioneine (ET/ ERGO) a natural diet-derived antioxidant was found to be a specific substrate of OCTN1 3.OCTN1 is functionally expressed in neurons and neural stem cells and activation of the transporter could conceivably have a protective role in neurodegenerative diseases. In addition, in peripheral organs, mutations in OCTN1 are associated with susceptibility to Crohn's disease and rheumatoid arthritis suggesting that OCTN1 may play a role in inflammatory dieseases 1.
Alternative names: Organic Cation/Carnitine Transporter 1, Ergothioneine Transporter, Solute Carrier Family 22 Member 4 -
基因ID
- 30805
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NCBI登录号
- NM_003059
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UniProt
- Q9Z306
抗原
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