SLC2A3 抗体 (Extracellular)
Quick Overview for SLC2A3 抗体 (Extracellular) (ABIN7043696)
抗原
See all SLC2A3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-52, Extracellular
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原理
- A Rabbit Polyclonal Antibody to Glucose Transporter 3
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特异性
- 1st extracellular loop
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交叉反应
- 小鼠, 大鼠
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交叉反应 （详细）
- Will not recognize human GLUT3.
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预测反应
- Mouse - identical
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产品特性
- Anti-GLUT3 (extracellular) Antibody (ABIN7043696, ABIN7044485 and ABIN7044486) is a highly specific antibody directed against an epitope of the rat Glucose Transporter 3 protein. The antibody can be used in western blot, immunohistochemistry, and live cell flow cytometry applications. The antibody has been designed to recognize GLUT3 from rat and mouse samples. It will not recognize GLUT3 from human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KDFLNYTLEERLED, corresponding to amino acid residues 39-52 of rat Glucose Transporter 3
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亚型
- IgG
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anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) (C-Term) antibody
SLC2A3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) antibodySLC2A3 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) (AA 150-250) antibodySLC2A3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) (C-Term) antibodySLC2A3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) (AA 205-269) antibodySLC2A3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) (AA 432-463) antibodySLC2A3 适用: 人, 大鼠, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB56266 unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) antibodySLC2A3 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) antibodySLC2A3 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) antibodySLC2A3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3) (AA 181-230) antibodySLC2A3 适用: 人, Cow, 山羊, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:400
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说明
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Negative Control: (ABIN7237002)
Blocking Peptide: (ABIN7237002)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- SLC2A3 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3))
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别名
- SLC2A3
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背景
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Glucose transporter 3, Facilitated glucose transporter member 3, SLC2A3,The GLUT protein family is encoded by the SLC2 genes and are a member of the major facilitator superfamily of membrane transporters. GLUTs are recognized as key regulators of whole-body glucose homeostasis, and are responsible for the uptake of carbohydrate-derived glucose by cells. There are 14 GLUT isoforms divided into 3 different group classes based on sequence similarity and structural and functional characteristics1,2.GLUT3 is a low-Km protein responsible for glucose uptake into neurons. It is predominantly expressed in neurons and is commonly called "neuronal glucose transporter". The protein contains 12 membrane-spanning domains, an N-linked glycosylation site in loop 1 responsible for high-affinity transport of glucose, and intracellular NH2- and COOH- termini. In addition, there are several conserved residues and motifs designated "sugar transporter signatures"1,2.GLUT3 levels are high in some malignant glioma cells compared to normal glial cells and therefore may be used as a therapeutic target in some cancer treatment3.
Alternative names: GLUT3, Glucose transporter 3, Facilitated glucose transporter member 3, SLC2A3 -
基因ID
- 100909595
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NCBI登录号
- NM_006931
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UniProt
- Q07647
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途径
- Warburg Effect
抗原
-
