SLC2A2 抗体 (Intracellular)
Our Local Distributor
北京 101111
Quick Overview for SLC2A2 抗体 (Intracellular) (ABIN7043694)
抗原
See all SLC2A2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 496-508, Intracellular
-
原理
- A Rabbit Polyclonal Antibody to Glucose Transporter 2
-
特异性
- Intracellular, C-terminus
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Mouse - identical, human - 8,13 amino acid residues identical
-
产品特性
- Anti-GLUT2 (SLC2A2) Antibody (ABIN7043694, ABIN7044483 and ABIN7044484) is a highly specific antibody directed against an epitope of the rat Glucose Transporter 2 protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GLUT2 from human, mouse, and rat samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: (C)EFRKKSGSAPPRK, corresponding to amino acid residues 496-508 of rat Glucose Transporter 2
-
亚型
- IgG
-
-
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) antibody
SLC2A2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (C-Term) antibodySLC2A2 适用: 人, 小鼠 WB, ELISA, IHC, IF, FLISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 482-524) antibodySLC2A2 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (N-Term) antibodySLC2A2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 277-290) antibodySLC2A2 适用: 人 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (N-Term) antibodySLC2A2 适用: 人, 大鼠, 小鼠, Pig, Cow, 犬, 豚鼠, 马, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 31-60) antibodySLC2A2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 31-60), (N-Term) antibodySLC2A2 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) (AA 67-174) antibodySLC2A2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200-1:400
-
说明
-
Negative Control: (ABIN7236998)
Blocking Peptide: (ABIN7236998)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW).
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))
-
别名
- SLC2A2
-
背景
-
Glucose transporter 2, Facilitated glucose transporter member 2,The GLUT protein family is encoded by SLC2 genes and is a member of the major facilitator superfamily of membrane transporters. The GLUT proteins contain 12 membrane-spanning domains, an N-linked glycosylation site, and intracellular NH2 and COOH termini, in addition to several conserved residues and motifs designated "sugar transporter signatures".Fourteen GLUT isoforms have been identified and divided into 3 different group classes based on sequence similarity and structural and functional characteristics. GLUT2 together with GLUT 1,3,4 and 14 belongs to Class I group1.GLUT2 acts as a facilitative glucose transporter in the liver, pancreas, intestine, kidney, and brain and is able to process high sugar concentrations. Due to the transporter's low affinity and high capacity, it guaranties large bidirectional fluxes of glucose in and out of the cell. GLUT2 also can transport other dietary sugars including fructose and galactose, when they are present in physiological concentrations2.GLUT2 mutations cause a severe and rare syndrome called Fanconi-Bickel, an autosomal recessive disorder in carbohydrate metabolism. Patients with Fanconi-Bickel disorder suffer from hepatomegaly, nephropathy, fasting hypoglycemia, sugar intolerance, and growth retardation. In addition, a GLUT2 polymorphism has been associated with preferences for sugary food2.
Alternative names: GLUT2 (SLC2A2), Glucose transporter 2, Facilitated glucose transporter member 2 -
基因ID
- 25351
-
NCBI登录号
- NM_000340
-
UniProt
- P12336
-
途径
- Warburg Effect
抗原
-
