Septin 7 抗体 (Intracellular)
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Quick Overview for Septin 7 抗体 (Intracellular) (ABIN7043614)
抗原
See all Septin 7 (SEPT7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 83-96, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Septin-7
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,human - identical
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产品特性
- Anti-Septin-7 Antibody (ABIN7043614, ABIN7044544 and ABIN7044545) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize Septin-7 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- Peptide (C)HRIKKTVQVEQSK, corresponding to amino acid residues 83-96 of rat Septin-7
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亚型
- IgG
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anti-Septin 7 (SEPT7) (AA 1-351) antibody
SEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 387-437) antibodySEPT7 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) antibodyKD Validated SEPT7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4470 unconjugated Recombinant Antibody
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 308-437) antibodySEPT7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) antibodySEPT7 适用: 人 WB, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 201-300) antibodySEPT7 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236776)
Blocking Peptide: (ABIN7236776)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Septin 7 (SEPT7)
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别名
- SEPTIN7
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背景
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Synonyms: Sept7, CDC10, SEPT7A, NBLA02942, CDC3
Description: Septin 7 is a highly conserved GTP-binding filamentous protein. Septins are important for the organization of the actin cytoskeleton. Septin7 also plays an important role in cytokinesis, and membrane dynamics1,2.Septins were first discovered in yeast and since, 13 septin genes have been identified in mammals (SEPT1 to SEPT12 and SEPT14). The 13 gene-encoded proteins can be classified into four distinct subgroups based on their sequence homology of their domain structure2.Septins share a highly conserved structure composed of the central GTPase domain and N- and C-terminal domains of various lengths3. They self-assemble into higher-order structures, including filaments and rings in tri-, hexa-, or octameric complexes consisting of multiple septin polypeptides, which are typical for different cell types. The various septin isoforms seem to determine the function and regulation of the septin complex4.Septin-7 regulates Ca2+ entry through Orai1 by regulating the opening of the channel5.Dysregulation of septins leads to human diseases such as neurodegenerative and bleeding disorders. In non-dividing cells such as neuronal tissue and platelets septins have been associated with exocytosis1,2.
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基因ID
- 64551
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NCBI登录号
- NM_001788
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UniProt
- Q9WVC0
抗原
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