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- 抗原 See all Septin 7 (SEPT7) 抗体
- Septin 7 (SEPT7)
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抗原表位
- AA 83-96, Intracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Septin 7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- A Rabbit Polyclonal Antibody to Septin-7
- 特异性
- Intracellular
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse,human - identical
- 产品特性
- Anti-Septin-7 Antibody (ABIN7043614, ABIN7044544 and ABIN7044545) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize Septin-7 from human, rat, and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: Peptide (C)HRIKKTVQVEQSK, corresponding to amino acid residues 83-96 of rat Septin-7
- 亚型
- IgG
- Top Product
- Discover our top product SEPT7 Primary Antibody
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anti-Septin 7 (SEPT7) antibody
SEPT7 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 308-437) antibodySEPT7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) antibodySEPT7 适用: 人 WB, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠, Cow WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 201-300) antibodySEPT7 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 1-418) antibodySEPT7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7236776)
Blocking Peptide: (ABIN7236776)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Septin 7 (SEPT7)
- 别名
- SEPTIN7 (SEPT7 产品)
- 背景
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Sept7, CDC10, SEPT7A, NBLA02942, CDC3,Septin 7 is a highly conserved GTP-binding filamentous protein. Septins are important for the organization of the actin cytoskeleton. Septin7 also plays an important role in cytokinesis, and membrane dynamics1,2.Septins were first discovered in yeast and since, 13 septin genes have been identified in mammals (SEPT1 to SEPT12 and SEPT14). The 13 gene-encoded proteins can be classified into four distinct subgroups based on their sequence homology of their domain structure2.Septins share a highly conserved structure composed of the central GTPase domain and N- and C-terminal domains of various lengths3. They self-assemble into higher-order structures, including filaments and rings in tri-, hexa-, or octameric complexes consisting of multiple septin polypeptides, which are typical for different cell types. The various septin isoforms seem to determine the function and regulation of the septin complex4.Septin-7 regulates Ca2+ entry through Orai1 by regulating the opening of the channel5.Dysregulation of septins leads to human diseases such as neurodegenerative and bleeding disorders. In non-dividing cells such as neuronal tissue and platelets septins have been associated with exocytosis1,2.
Alternative names: Sept7, CDC10, SEPT7A, NBLA02942, CDC3 - 基因ID
- 64551
- NCBI登录号
- NM_001788
- UniProt
- Q9WVC0
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