RIC3 抗体 (Intracellular)
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Quick Overview for RIC3 抗体 (Intracellular) (ABIN7043599)
抗原
See all RIC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-174, Intracellular
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原理
- A Rabbit Polyclonal Antibody to RIC-3
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特异性
- Intracellular, C-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,human - identical
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产品特性
- Anti-RIC3 Antibody (ABIN7043599, ABIN7044633 and ABIN7044634) is a highly selective antibody directed against an epitope of mouse protein . The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize RIC3 from human, mouse, and rat samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)EKLINRVGPNGESR, corresponding to amino acid residues 161-174 of mouse RIC3
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亚型
- IgG
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anti-Resistance To Inhibitors of Cholinesterase 3 Homolog (RIC3) antibody
RIC3 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 3 Homolog (RIC3) (AA 1-368) antibodyRIC3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 3 Homolog (RIC3) (AA 313-341), (C-Term) antibodyRIC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32321 unconjugated
anti-Resistance To Inhibitors of Cholinesterase 3 Homolog (RIC3) (AA 319-348), (C-Term) antibodyRIC3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:400
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7236722)
Blocking Peptide: (ABIN7236722)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- RIC3 (Resistance To Inhibitors of Cholinesterase 3 Homolog (RIC3))
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别名
- RIC3
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背景
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Protein RIC-3, RIC3 acetylcholine receptor chaperone, Resistant to inhibitor of cholinesterase 3,RIC-3 (Resistance to inhibitors of cholinesterase 3) is a conserved endoplasmic reticulum-resident protein that is known to be a chaperone for the nicotinic acetylcholine receptors (nAChR) and for the serotonin (5-HT3) channels1.RIC-3 affects the maturation of multiple nAChRs which has been shown to facilitate nAChR assembly and trafficking3,4.Multiple transcripts of RIC-3 displaying differential expression are detected in humans. The full-length transcript includes two transmembrane domains followed by a coiled-coil domain, a nonconserved N-terminus and C-terminus domain, which includes a second coiled-coil domain. The short isoform lacks the coiled-coil domains and is very conserved in mammals1,2,4.
Alternative names: RIC3, Protein RIC-3, RIC3 acetylcholine receptor chaperone, Resistant to inhibitor of cholinesterase 3 -
基因ID
- 320360
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NCBI登录号
- NM_024557
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UniProt
- Q8BPM6
抗原
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