KCNK6 抗体 (C-Term, Intracellular)
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Quick Overview for KCNK6 抗体 (C-Term, Intracellular) (ABIN7043447)
抗原
See all KCNK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 295-313, C-Term, Intracellular
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原理
- A Rabbit Polyclonal Antibody to KCNK6 Channel
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交叉反应
- 人, 大鼠
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预测反应
- Rat - 13,17 amino acid residues identical
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产品特性
- Anti-KCNK6 Antibody (ABIN7043447 and ABIN7044950) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot analysis. It has been designed to recognize KCNK6 from rat and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)ESHQQLSASSHTDYASIPR, corresponding to residues 295-313 of human KCNK6
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亚型
- IgG
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anti-Potassium Channel Subfamily K Member 6 (KCNK6) (C-Term) antibody
KCNK6 适用: 人, 大鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 6 (KCNK6) (AA 263-292), (C-Term) antibodyKCNK6 适用: 人 WB 宿主: 兔 Polyclonal RB32356 unconjugated
anti-Potassium Channel Subfamily K Member 6 (KCNK6) (N-Term) antibodyKCNK6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 6 (KCNK6) (AA 254-313) antibodyKCNK6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 6 (KCNK6) (AA 71-120) antibodyKCNK6 适用: 人, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236299)
Blocking Peptide: (ABIN7236299)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- KCNK6 (Potassium Channel Subfamily K Member 6 (KCNK6))
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别名
- KCNK6
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背景
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Synonyms: Potassium channel subfamily K member 6, TOSS, K2P6.1
Description: KCNK6 (also named Tandem of P domain of Weak Inward rectifier K+ channel 2, TWIK-2 or K2P6.1) is a member of the 2-pore (2P) domain K+ channel family that includes at least 16 members. These channels show little time- or voltage-dependence and are considered to be "leak" or "background" K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation.The K2P channels have a signature topology that includes four transmembrane domains and two pore domains with intracellular N- and C- termini. The functional channel is believed to be a dimer.K2P channels are regulated by diverse physical and chemical stimuli including temperature, changes in intracellular pH , mechanical stretch, inhalation anesthetics, etc. The channels can then be subclassified based in their specific activators.KCNK6 displays low single channel conductance of about 5pS and is partially activated by arachidonic acid and blocked by volatile anesthetics.KCNK6 expression is widespread, especially in the rat were it is expressed in brain, heart, kidney and liver. In humans KCNK6 expression is more restricted with expression in aorta, stomach, placenta and spleen while in mouse, KCNK6 expression has been detected only in liver.
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基因ID
- 9424
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NCBI登录号
- NM_004823
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UniProt
- Q9Y257
抗原
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