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- 抗原 See all KCNK6 抗体
- KCNK6 (Potassium Channel Subfamily K Member 6 (KCNK6))
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抗原表位
- AA 295-313, Intracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNK6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- A Rabbit Polyclonal Antibody to KCNK6 Channel
- 特异性
- Intracellular, C-terminus
- 交叉反应
- 人, 大鼠
- 预测反应
- Rat - 13,17 amino acid residues identical
- 产品特性
- Anti-KCNK6 Antibody (ABIN7043447 and ABIN7044950) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot analysis. It has been designed to recognize KCNK6 from rat and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)ESHQQLSASSHTDYASIPR, corresponding to residues 295-313 of human KCNK6
- 亚型
- IgG
- Top Product
- Discover our top product KCNK6 Primary Antibody
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anti-Potassium Channel Subfamily K Member 6 (KCNK6) (C-Term) antibody
KCNK6 适用: 人, 大鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 6 (KCNK6) (AA 71-120) antibodyKCNK6 适用: 人, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 6 (KCNK6) (AA 254-313) antibodyKCNK6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 6 (KCNK6) (N-Term) antibodyKCNK6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 6 (KCNK6) (AA 263-292), (C-Term) antibodyKCNK6 适用: 人 WB 宿主: 兔 Polyclonal RB32356 unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7236299)
Blocking Peptide: (ABIN7236299)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- KCNK6 (Potassium Channel Subfamily K Member 6 (KCNK6))
- 别名
- KCNK6 (KCNK6 产品)
- 背景
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Potassium channel subfamily K member 6, TOSS, K2P6.1,KCNK6 (also named Tandem of P domain of Weak Inward rectifier K+ channel 2, TWIK-2 or K2P6.1) is a member of the 2-pore (2P) domain K+ channel family that includes at least 16 members. These channels show little time- or voltage-dependence and are considered to be "leak" or "background" K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation.The K2P channels have a signature topology that includes four transmembrane domains and two pore domains with intracellular N- and C- termini. The functional channel is believed to be a dimer.K2P channels are regulated by diverse physical and chemical stimuli including temperature, changes in intracellular pH , mechanical stretch, inhalation anesthetics, etc. The channels can then be subclassified based in their specific activators.KCNK6 displays low single channel conductance of about 5pS and is partially activated by arachidonic acid and blocked by volatile anesthetics.KCNK6 expression is widespread, especially in the rat were it is expressed in brain, heart, kidney and liver. In humans KCNK6 expression is more restricted with expression in aorta, stomach, placenta and spleen while in mouse, KCNK6 expression has been detected only in liver.
Alternative names: KCNK6 (TWIK-2), Potassium channel subfamily K member 6, TOSS, K2P6.1 - 基因ID
- 9424
- NCBI登录号
- NM_004823
- UniProt
- Q9Y257
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