Plexin C1 抗体 (Extracellular)
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- 抗原 See all Plexin C1 (PLXNC1) 抗体
- Plexin C1 (PLXNC1)
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抗原表位
- AA 860-874, Extracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Plexin C1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal antibody to Plexin-C1 (extracellular)
- 特异性
- Extracellular, N-terminus.
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse - identical Rat - 14 out of 15 amino acid residues identical
- 产品特性
- A rabbit polyclonal antibody to Plexin-C1 (extracellular)
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: Peptide (C)EVKIQKENDNFNISK, corresponding to amino acid residues 860 - 874 of human Plexin-C1
- 亚型
- IgG
- Top Product
- Discover our top product PLXNC1 Primary Antibody
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anti-Plexin C1 (PLXNC1) (AA 35-234) antibody
PLXNC1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2H11C11 unconjugated
anti-Plexin C1 (PLXNC1) antibodyPLXNC1 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Plexin C1 (PLXNC1) (Internal Region) antibodyPLXNC1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Plexin C1 (PLXNC1) (Internal Region) antibodyPLXNC1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Plexin C1 (PLXNC1) (AA 81-218) antibodyPLXNC1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Plexin C1 (PLXNC1) (AA 250-348) antibodyPLXNC1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Plexin C1 (PLXNC1) (AA 250-348) antibodyPLXNC1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1A12 unconjugated
anti-Plexin C1 (PLXNC1) (AA 1025-1054) antibodyPLXNC1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Plexin C1 (PLXNC1) (AA 1025-1054), (C-Term) antibodyPLXNC1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32646 unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7236272)
Blocking Peptide: (ABIN7236272)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Plexin C1 (PLXNC1)
- 别名
- PLXNC1 (PLXNC1 产品)
- 背景
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Virus-Encoded Semaphorin Protein Receptor, VESPR, CD232, PLXNC1,Plexin-C1 also known as Virus-encoded semaphorin protein receptor, is a ~210 kDa type I transmembrane receptor that regulates cytoskeletal remodeling and adhesion in human melanocytes.It belongs to the family of Plexin receptors, these are type I transmembrane proteins (A-D) that share a highly conserved cytoplasmic domain and an intracellular region containing an intrinsic Ras-GTPase activating (GAP) domain. Plexin receptors bind semaphorins: a class of secreted and membrane proteins 1. The natural ligand of Plexin C1 is Semaphorin -7A (#ASR-077).Plexin-C1 is highly expressed in melanocytes, neurons, neutrophils, dendritic cells and pre-osteoblasts and it has a complex effect on migration of melanocytes and melanoma, that depends on the phase of progression of this type of cancer 2,3. It also has additional roles in the partitioning of paraventricular and supraoptic neurons in the hypothalamus, in the development of inflamation and in inhibition of neutrophils phagocytosis 3,4.
Alternative names: Virus-Encoded Semaphorin Protein Receptor, VESPR, CD232, PLXNC1 - 基因ID
- 10154
- NCBI登录号
- NM_005761
- UniProt
- O60486
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