Plexin A1 抗体 (Extracellular) (FITC)
Quick Overview for Plexin A1 抗体 (Extracellular) (FITC) (ABIN7043436)
抗原
See all Plexin A1 (PLXNA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 623-636, Extracellular
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原理
- A Rabbit Polyclonal Antibody to Plexin-A1 Conjugated to the Fluorescent Dye FITC
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特异性
- Extracellular, N-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,rat - 13,14 amino acid residues identical
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产品特性
- Anti-Plexin-A1 (extracellular) Antibody (ABIN7043435, ABIN7045128 and ABIN7045129) is a highly specific antibody directed against an extracellular epitope of the human protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize PLXNA1 from mouse, rat, and human samples. \nAnti-Plexin-A1 (extracellular)-FITC Antibody (ABIN7043435, ABIN7045128 and ABIN7045129)-F) is directly conjugated to fluorescein isothiocyanate (FITC). This labeled antibody can be used in immunofluorescent applications such as direct live cell flow cytometry.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)REVAPITRGQGDQR, corresponding to amino acid residues 623-636 of human PLXNA1
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亚型
- IgG
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anti-Plexin A1 (PLXNA1) (AA 1100-1200) antibody
PLXNA1 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8A10A6 unconjugated
anti-Plexin A1 (PLXNA1) (AA 1100-1200) antibodyPLXNA1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7B8H9 unconjugated
anti-Plexin A1 (PLXNA1) antibodyPLXNA1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 43-300) antibodyPLXNA1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 623-636), (Extracellular) antibodyPLXNA1 适用: 人 WB, IHC, FACS, LCI, IF 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 901-1000) antibodyPLXNA1 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 32-296) antibodyPLXNA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: N/A
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说明
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Negative Control: (ABIN7582044)
Blocking Peptide: (ABIN7236260)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Plexin A1 (PLXNA1)
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别名
- PLXNA1
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背景
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PLXNA1, PLXN1, Semaphorin receptor NOV,The plexin family are transmembrane receptors, comprises four subfamilies- plexin-A, B, C, and D. In human, three members of the plexin-A subfamily have been isolated- plexin-A1, A2, and A3. Plexin A1 is encoded by the PLXNA1 gene.These receptors are characterized by the presence of a conserved intracellular domain of about 600 amino acids known as the sex and plexins domain. This domain is strikingly conserved across the plexin family and consists of two blocks of high sequence conservation separated by a variable linker. The ectodomains of the plexin-A subfamily possess three repeats of the cysteine cluster/Met-Related Sequences.Plexins act as signal-transducing components containing transmembrane domain of six Gly residues constituting a GxGGGGG motif.Plexins act as functional receptors for members of the semaphorin family. Together they transmit repulsive axon guidance signals for semaphorins inside the axonal growth cone. The plexins act together with their co-receptors, neuropilins. Plexin-A1, in combination with neuropilins exhibits various functions in axon guidance, organogenesis, angiogenesis, tumorigenesis, and immune regulation1-3.Plexin-A1 also plays an important role in the developmental stages of chick heart by working as a receptor for one of the transmembrane semaphorins. In addition Plexin-A1 expressed in dendritic cells is involved in T-dendritic cell interactions in the immune system4.
Alternative names: Plexin-A1, PLXNA1, PLXN1, Semaphorin receptor NOV -
基因ID
- 5361
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NCBI登录号
- NM_032242
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UniProt
- Q9UIW2
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途径
- Smooth Muscle Cell Migration
抗原
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