Oxytocin Receptor 抗体 (C-Term, Intracellular)
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Quick Overview for Oxytocin Receptor 抗体 (C-Term, Intracellular) (ABIN7043419)
抗原
See all Oxytocin Receptor (OXTR) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 346-358, C-Term, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Oxytocin Receptor
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交叉反应
- 小鼠, 大鼠
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交叉反应 （详细）
- Not recommended for use with human samples.
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预测反应
- Mouse - identical
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产品特性
- Anti-Oxytocin Receptor Antibody is directed against an epitope of the rat Oxytocin receptor. Anti-Oxytocin Receptor Antibody (ABIN7043419, ABIN7045341 and ABIN7045342) can be used in western blot analysis. It has been designed to recognize the oxytocin receptor from rat and mouse samples. The antibody is not recommended for use with human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- CSARYLKGSRPGE, corresponding to amino acid residues 346-358 of rat Oxtr
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亚型
- IgG
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anti-Oxytocin Receptor (OXTR) (AA 325-388) antibody
OXTR 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (AA 6-75) antibodyOXTR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (Internal Region) antibodyVerified OXTR 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) antibodyOXTR 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB560 unconjugated Recombinant Antibody
anti-Oxytocin Receptor (OXTR) (AA 348-380), (C-Term) antibodyOXTR 适用: 人 WB 宿主: 兔 Polyclonal RB52104 unconjugated
anti-Oxytocin Receptor (OXTR) antibodyOXTR 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (AA 272-377) antibodyOXTR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (AA 43-129) antibodyOXTR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (AA 1-36) antibodyOXTR 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) antibodyOXTR 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
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说明
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Cited Application: IP|IHC|ICC
Negative Control: (ABIN7236202)
Blocking Peptide: (ABIN7236202)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Oxytocin Receptor (OXTR)
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别名
- OXTR
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背景
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Synonyms: OXTR, OT-R, OTR1
Description: Oxytocin receptor belongs to the class 1 family of G-protein coupled receptors (GPCR) and its role is to regulate reproductive physiology, social and emotional behaviors. Like other members belonging to the GPCR superfamily, it has seven transmembrane domains, extracellular N-terminus and intracellular C-terminal tail1,2.The Oxytocin receptor ligand oxytocin, is a peptide that functions both as a hormone and as a neurotransmitter, and plays an important role in social behavior, estrous cycle, induction of labor and milk ejection, anxiety-related behaviors, food intake, stress-related responses, and pain control. Activation of the receptor leads to the stimulation of phospholipase C by interacting with Gαq/11 in response to ligand binding1.Oxytocin receptor is widely abundant in several brain regions including the basal ganglia, the limbic system, the thalamus, the hypothalamus, the brainstem, and the spinal cord. It is also detected in the uterus, mammary gland, ovary, testis, prostate and kidney.Several studies have suggested that administration of oxytocin in humans has the ability to increase generosity, trust and eye gaze. Oxytocin levels in the plasma relates to parent-child bonding behaviors, feelings of romantic love, trust and empathy. Similarly, Oxytocin receptor knockout mice shows several abnormalities in social and emotional behavior such as increased aggression and deficits in nurturing, positive affection, attachment, sensitivity and social memory2,3.
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基因ID
- 25342
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NCBI登录号
- NM_000916
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UniProt
- P70536
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途径
- Myometrial Relaxation and Contraction, Feeding Behaviour
抗原
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