Oxytocin Receptor 抗体 (Intracellular)
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- 抗原 See all Oxytocin Receptor (OXTR) 抗体
- Oxytocin Receptor (OXTR)
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抗原表位
- AA 346-358, Intracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Oxytocin Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to Oxytocin Receptor
- 特异性
- Intracellular, C-terminus
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 （详细）
- Not recommended for use with human samples.
- 预测反应
- Mouse - identical
- 产品特性
- Anti-Oxytocin Receptor Antibody is directed against an epitope of the rat Oxytocin receptor. Anti-Oxytocin Receptor Antibody (ABIN7043419, ABIN7045341 and ABIN7045342)) can be used in western blot analysis. It has been designed to recognize the oxytocin receptor from rat and mouse samples. The antibody is not recommended for use with human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 质量等级
- KO Validated
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: CSARYLKGSRPGE, corresponding to amino acid residues 346-358 of rat Oxtr
- 亚型
- IgG
- Top Product
- Discover our top product OXTR Primary Antibody
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anti-Oxytocin Receptor (OXTR) (AA 325-388) antibody
OXTR 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (AA 6-75) antibodyOXTR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (Internal Region) antibodyVerified OXTR 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (AA 348-380), (C-Term) antibodyOXTR 适用: 人 WB 宿主: 兔 Polyclonal RB52104 unconjugated
anti-Oxytocin Receptor (OXTR) (AA 272-377) antibodyOXTR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (AA 1-36) antibodyOXTR 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) (AA 43-129) antibodyOXTR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) antibodyOXTR 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oxytocin Receptor (OXTR) antibodyOXTR 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
- 说明
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Cited Application: IP|IHC|ICC
Negative Control: BLP-VR013
Blocking Peptide: BLP-VR013
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Oxytocin Receptor (OXTR)
- 别名
- OXTR (OXTR 产品)
- 背景
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OXTR, OT-R, OTR1,Oxytocin receptor belongs to the class 1 family of G-protein coupled receptors (GPCR) and its role is to regulate reproductive physiology, social and emotional behaviors. Like other members belonging to the GPCR superfamily, it has seven transmembrane domains, extracellular N-terminus and intracellular C-terminal tail1,2.The Oxytocin receptor ligand oxytocin, is a peptide that functions both as a hormone and as a neurotransmitter, and plays an important role in social behavior, estrous cycle, induction of labor and milk ejection, anxiety-related behaviors, food intake, stress-related responses, and pain control. Activation of the receptor leads to the stimulation of phospholipase C by interacting with Gαq/11 in response to ligand binding1.Oxytocin receptor is widely abundant in several brain regions including the basal ganglia, the limbic system, the thalamus, the hypothalamus, the brainstem, and the spinal cord. It is also detected in the uterus, mammary gland, ovary, testis, prostate and kidney.Several studies have suggested that administration of oxytocin in humans has the ability to increase generosity, trust and eye gaze. Oxytocin levels in the plasma relates to parent-child bonding behaviors, feelings of romantic love, trust and empathy. Similarly, Oxytocin receptor knockout mice shows several abnormalities in social and emotional behavior such as increased aggression and deficits in nurturing, positive affection, attachment, sensitivity and social memory2,3.
Alternative names: Oxytocin Receptor, OXTR, OT-R, OTR1 - 基因ID
- 25342
- NCBI登录号
- NM_000916
- UniProt
- P70536
- 途径
- Myometrial Relaxation and Contraction, Feeding Behaviour
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