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SLC22A3 抗体 (Extracellular)

OCT3 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7043416
发货至: 中国
  • 抗原 See all SLC22A3 (OCT3) 抗体
    SLC22A3 (OCT3) (Organic Cation Transporter 3 (OCT3))
    抗原表位
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 83-96, Extracellular
    适用
    • 33
    • 15
    • 14
    • 4
    • 4
    • 1
    • 1
    大鼠
    宿主
    • 31
    • 2
    • 1
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SLC22A3 antibody is un-conjugated
    应用范围
    • 18
    • 11
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    A Rabbit Polyclonal Antibody to Organic Cation Transporter 3
    特异性
    1st extracellular loop
    交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    Not recommended for human samples.
    预测反应
    Rat,mouse - 13,14 amino acid residues identical
    产品特性
    Anti-SLC22A3 (extracellular) Antibody (ABIN7043416, ABIN7044223 and ABIN7044224) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize Organic cation transporter 3 from rat and mouse samples. The antibody is unlikely to recognize the protein from human samples.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)ERRGQGH(S)HRYLLE, corresponding to amino acid residues 83-96 of rat OCT3

    亚型
    IgG
    Top Product
    Discover our top product OCT3 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200

    Application Dilutions Western blot wb: 1:200

    说明

    Negative Control: (ABIN7236191)

    Blocking Peptide: (ABIN7236191)

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    0.2 mL double distilled water (DDW).
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    SLC22A3 (OCT3) (Organic Cation Transporter 3 (OCT3))
    别名
    SLC22A3 (OCT3 产品)
    背景
    OCT3, Organic cation transporter 3,Organic cation transporter 3 (SLC22A3) belongs to the SLC22A gene family. Organic cation transporters (OCTs) are membrane transport proteins involved in many metabolic processes and detoxification. The transporters are responsible for the uptake and intracellular inactivation of numerous endogenous and exogenous substrates including norepinephrine, epinephrine, dopamine, histamine and serotonin. They are also responsible for the uptake of a variety of anticancer drugs1,2. OCT structure is suggested to have 12 transmembrane domains and a large hydrophobic cleft capable of accommodating a wide variety of chemical species3.In humans, OCT3 is expressed in many tissues, abundantly in the placenta, heart, liver and skeletal muscle. It is also expressed in astrocytes, intestinal epithelium neurons, glia, ependymal cells, and blood-cerebrospinal fluid barrier in choroid plexus epithelial cells. The protein is also widely distributed in the brain. OCT expression is detected in several cancer cell lines and tumor tissue samples1-3.

    Alternative names: SLC22A3, OCT3, Organic cation transporter 3
    基因ID
    29504
    NCBI登录号
    NM_021977
    UniProt
    O88446
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