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NRP2 抗体 (Extracellular) (FITC)

NRP2 适用: 人 FACS 宿主: 兔 Polyclonal FITC
产品编号 ABIN7043381
发货至: 中国
  • 抗原 See all NRP2 抗体
    NRP2 (Neuropilin 2 (NRP2))
    抗原表位
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 747-758, Extracellular
    适用
    • 41
    • 21
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 3
    • 1
    克隆类型
    • 44
    • 3
    多克隆
    标记
    • 26
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NRP2 antibody is conjugated to FITC
    应用范围
    • 33
    • 20
    • 12
    • 5
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    原理
    A Rabbit Polyclonal Antibody to Neuropilin-2 Conjugated to the Fluorescent Dye FITC
    特异性
    Extracellular, N-terminus
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Rat,mouse - 11,12 amino acid residues identical
    产品特性
    Anti-Neuropilin-2 (NRP2) (extracellular) Antibody (ABIN7043380, ABIN7044700 and ABIN7044701)) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot, immunohistochemistry, and indirect flow cytometry applications. The antibody recognizes an extracellular epitope and is thus ideal for detecting the protein in living cells. It has been designed to recognize NRP2 from mouse, rat, and human samples. \nAnti-Neuropilin-2 (NRP2) (extracellular)-FITC Antibody (ABIN7043380, ABIN7044700 and ABIN7044701)-F) is directly conjugated to fluorescein isothiocyanate (FITC). This labeled antibody can be used in immunofluorescent applications such as direct live cell flow cytometry.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)REDQGGEWKHGR, corresponding to amino acid residues 747-758 of human neuropilin-2

    亚型
    IgG
    Top Product
    Discover our top product NRP2 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

    Application Dilutions Western blot wb: N/A

    说明

    Negative Control: RIC-001-F

    Blocking Peptide: BLP-NR062

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    NRP2 (Neuropilin 2 (NRP2))
    别名
    NRP2 (NRP2 产品)
    背景
    Vascular endothelial cell growth factor 165 receptor 2, VEGF165R2,The neuropilins (NRPs) are single-pass multifunctional transmembrane glycoproteins that play an important role in cell development, immunity and cancer, and physiological and pathological angiogenesis. They were first discovered as regulators of nervous system development, acting as semaphorin co-receptors with plexins, as well as enhancers of cellular responses to members of the vascular endothelial growth factor (VEGF) family.The NRP family comprises two members: Neuropilin-1 (NRP1) and Neuropilin-2 (NRP2), which are usually expressed as homodimers but can also appear as heterodimers. NRP2 contains a large extracellular N-terminal which consists of five domains, a short transmembrane domain and a small cytoplasmic domain1-3. NRP2 is expressed in a wide variety of cells including endothelial cells, neurons, pancreatic islet cells, hepatocytes, melanocytes and osteoblasts. NRP2 has been shown to mediate proliferation, survival, and migration of tumor cells3.NRP2 knockout mice studies show that mice are viable without defects in blood vessels but display abnormal lymphatic development and defects of the central and peripheral nervous systems2.

    Alternative names: Neuropilin-2 (NRP2), Vascular endothelial cell growth factor 165 receptor 2, VEGF165R2
    基因ID
    8828
    NCBI登录号
    NM_003872
    UniProt
    O60462
    途径
    Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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