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Neuropilin 1 抗体 (Extracellular)

Name: Neuropilin 1 抗体 (Extracellular)
SKU: ABIN7043378
Availability: OutOfStock

This anti-Neuropilin 1 antibody is a 兔多克隆 antibody detecting Neuropilin 1 in WB, FACS, IF, IC 和 LCI. Suitable for 人.

Western blot analysis of human Jurkat T-cell leukemia cell line lysate: - 1. (Neuropilin 1 抗体 (Extracellular))

Cell surface detection of Neuropilin-1 by indirect flow cytometry in live intact mouse J774 macrophage cells: (black line) Cells. (Neuropilin 1 抗体 (Extracellular))

FACS

Expression of Neuropilin-1 in human U-87 MG cells - Cell surface detection of Neuropilin-1 in live intact human U-87 MG glioblastoma cells. (Neuropilin 1 抗体 (Extracellular))

ICC

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: - 1,2. (Neuropilin 1 抗体 (Extracellular))

4 images

产品编号 ABIN7043378

发货至: 中国

Datasheet as PDF

Quick Overview for Neuropilin 1 抗体 (Extracellular) (ABIN7043378)

抗原

See all Neuropilin 1 (NRP1) 抗体

Neuropilin 1 (NRP1)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Neuropilin 1 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunochromatography (IC), Live Cell Imaging (LCI)

Discover our top product NRP1 Primary Antibody

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AA 502-514, Extracellular

原理

A Rabbit Polyclonal Antibody to Neuropilin-1

特异性

Extracellular, N-terminus

交叉反应

人, 小鼠, 大鼠

预测反应

Rat,mouse - identical

产品特性

Anti-Neuropilin-1 (NRP1) (extracellular) Antibody (ABIN7043378, ABIN7044702 and ABIN7044703) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot, immunocytochemistry, and live cell imaging applications. It has been designed to recognize NRP1 from human, mouse, and rat samples.

纯化方法

Affinity purified on immobilized antigen.

免疫原

Immunogen: Synthetic peptide
Immunogen Sequence: (C)GGKHRENKVFMRK, corresponding to amino acid residues 502-514 of human neuropilin-1

亚型

IgG
anti-Neuropilin 1 (NRP1) (AA 646-814) antibody
NRP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Neuropilin 1 (NRP1) (AA 646-814) antibody
NRP1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated

anti-Neuropilin 1 (NRP1) (AA 22-131) antibody
NRP1 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated

anti-Neuropilin 1 (NRP1) (AA 21-250) antibody
NRP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Neuropilin 1 (NRP1) antibody
NRP1 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Neuropilin 1 (NRP1) (AA 722-750) antibody
NRP1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Neuropilin 1 (NRP1) (AA 45-59) antibody
NRP1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5B1E11 unconjugated

anti-Neuropilin 1 (NRP1) (AA 722-750), (C-Term) antibody
NRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22995 unconjugated

anti-Neuropilin 1 (NRP1) (AA 851-923) antibody
NRP1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Neuropilin 1 (NRP1) (AA 22-644) antibody
NRP1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5H11G6 unconjugated

应用备注

Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200

说明

Negative Control: (ABIN7236114)
Blocking Peptide: (ABIN7236114)

限制

仅限研究用
状态

Lyophilized

溶解方式

Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

浓度

1 mg/mL

缓冲液

PBS pH 7.4

储存条件

4 °C,-20 °C

储存方法

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
抗原

Neuropilin 1 (NRP1)

别名

NRP1

背景

Vascular endothelial cell growth factor 165 receptor, VEGF165R, CD304,Neuropilins (NRPs) are co-receptors for class 3 semaphorins, polypeptides with key roles in axonal guidance, and for members of the VEGF (vascular endothelial growth factor) family of angiogenic cytokines.Neuropilin 1 (NRP1) is a transmembrane glycoprotein and comprises a large extracellular region containing multiple domains, a single transmembrane domain and a small cytoplasmic domain, also with a number of protein interacting domains.Class 3 semaphorins bind NRP1 (and NRP2) with different, and partially overlapping, specificities and affinities. Plexin A1 and Plexin A2 are the major signaling receptors for class 3 semaphorins, and complex with NRPs and semaphorins to form a holoreceptor essential for mediating effects of semaphorins on growth-cone collapse and axonal guidance in neurogenesis. The major VEGF-A signaling receptor, VEGF receptor 2, forms complexes with NRP1 and is important for optimal VEGFR2 signaling and function in endothelial cells.Targeted disruption of the NRP1 gene has demonstrated an essential dual role of these molecules in neurogenesis and cardiovascular development. NRP1-null mice die with a spectrum of cardiovascular and neuronal defects1.

Alternative names: Neuropilin-1 (NRP1), Vascular endothelial cell growth factor 165 receptor, VEGF165R, CD304

基因ID

8829

NCBI登录号

NM_001024628

UniProt

O14786

途径

Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals