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- 抗原 See all NETO1 抗体
- NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))
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抗原表位
- AA 24-37, Extracellular
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NETO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to NETO1
- 特异性
- Extracellular, N-terminus
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Rat - identical, human - 12,14 amino acid residues identical
- 产品特性
- Anti-NETO1 (extracellular) Antibody (ABIN7043376, ABIN7044384 and ABIN7044385)) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot and immunohistochemistry applications. The antibody recognizes an extracellular epitope and can potentially be used for detecting the protein in living cells. It has been designed to recognize NETO1 from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KKGTEKQITPETQK, corresponding to amino acid residues 24-37 of mouse NETO1
- 亚型
- IgG
- Top Product
- Discover our top product NETO1 Primary Antibody
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anti-Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 367-507) antibody
NETO1 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 1-533) antibodyNETO1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 303-352) antibodyNETO1 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (C-Term) antibodyNETO1 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (C-Term) antibodyNETO1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: BLP-GC045
Blocking Peptide: BLP-GC045
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))
- 别名
- NETO1 (NETO1 产品)
- 背景
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Neuropilin and tolloid-like protein 1, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1, BCTL1, BTCL1,NETO proteins are auxiliary subunits that play crucial roles in modulating the biophysical properties of Kainate receptors (KARs) and N-methyl-D-aspartate receptors (NMDARs). NETO proteins modulate these receptors both in vivo and in vitro. NETO1 is also responsible for the slow kinetics of postsynaptic KAR-mediated currents and regulate synaptic recruitment of Kainate receptors1.NETO1 is a single transmembrane domain protein containing two extracellular CUB domains of about 110 amino acids, a low-density lipoprotein receptor domain, and a cytoplasmic tail of almost 167 amino acids that includes a C-terminal TRV class I PDZ binding motif2.NETO1 and NETO2, are highly homologous, but have a different expression patterns and distinct functional effects. NETO1 subunit is expressed in high levels in the developing hippocampus and regulates axonal and presynaptic Kainate receptors at the CA3-CA1 region of the hippocampus. NETO1 deficiency resulted in impairs synaptogenesis and disrupts synchronization of the CA3-CA1 neuronal populations1,3. NETO1 is enriched in the post-synaptic density where it co-localizes with post-synaptic density-95 (PSD-95) and GluN12.
Alternative names: NETO1, Neuropilin and tolloid-like protein 1, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1, BCTL1, BTCL1 - 基因ID
- 246317
- NCBI登录号
- NM_138999
- UniProt
- Q8R4I7
- 途径
- Regulation of long-term Neuronal Synaptic Plasticity
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