NPY5R 抗体 (3rd Intracellular Loop)
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Quick Overview for NPY5R 抗体 (3rd Intracellular Loop) (ABIN7043375)
抗原
See all NPY5R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 3rd Intracellular Loop, AA 291-306
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原理
- A Rabbit Polyclonal Antibody to Neuropeptide Y5 Receptor
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交叉反应
- 小鼠, 大鼠
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预测反应
- Mouse,bovine,canis - identical, human - 15,16 amino acid residues identical
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产品特性
- Anti-NPY5R Antibody is directed against an epitope of the rat neuropeptide Y5 receptor (NPY5R). Anti-NPY5R Antibody (ABIN7043375 and ABIN7044673) can be used in western blot, immunohistochemistry and immunocytochemistry applications. It has been designed to recognize NPY5R from rat, human and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- SFIRKHRRRYSKKTAC, corresponding to amino acid residues 291-306 of rat NPY5R
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亚型
- IgG
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anti-Neuropeptide Y Receptor Y5 (NPY5R) (Internal Region) antibody
Verified NPY5R 适用: 人, Hamster WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y5 (NPY5R) (Cytoplasmic Domain) antibodyNPY5R 适用: 人, 猴 IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y5 (NPY5R) (Cytoplasmic Domain) antibodyNPY5R 适用: 人 IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y5 (NPY5R) antibodyNPY5R 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Neuropeptide Y Receptor Y5 (NPY5R) antibodyNPY5R 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB60 unconjugated Recombinant Antibody
anti-Neuropeptide Y Receptor Y5 (NPY5R) (AA 1-445) antibodyNPY5R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y5 (NPY5R) (Cytoplasmic Domain) antibodyNPY5R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y5 (NPY5R) (AA 221-270) antibodyNPY5R 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y5 (NPY5R) (Center) antibodyNPY5R 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y5 (NPY5R) (AA 1-100) antibodyNPY5R 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: 1:100
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236102)
Blocking Peptide: (ABIN7236102)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))
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别名
- NPY5R
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背景
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Synonyms: Neuropeptide Y5 receptor, Neuropeptide Y receptor type 5, NPY Y5 receptor, NPYY5
Description: Neuropeptide Y (NPY) is a 36 amino acid peptide neurotransmitter present in the central and peripheral nervous systems.1 NPY is involved in the regulation of a broad range of functions such as eating behavior, hypertension, and reproduction.2NPY exerts its effects via five receptor subtypes known as the neuropeptide Y receptors (NPYR): Y1 (NPY1R), Y2 (NPY2R), Y4 (NPY4R), Y5 (NPY5R), and Y6 (NPY6R).2 Four of these (Y1, Y2, Y4, and Y5) are expressed in humans.2 The NPY receptors belong to the G protein-coupled receptor superfamily whose members share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus.Activation of these receptors by NPY affects [Ca2+]i, adenylate cyclase signalling, and a number of ion channel functions.3 Based on their high frequency and density in steroid hormone-producing tumors, the NPYRs might be of potential use in tumor management.2NPY5R as well as NPY1R and NPY2R are expressed in the hypothalamus, in the brain stem, and in peripheral tissues, such as blood vessels, lung, kidney, adrenal glands, stomach, colon, heart, pancreas, and intestine. NPY5R has been postulated as the mediator of the feeding response to NPY and related peptides (125 in Kamiji, M. M). Its localization in the brain is consistent with this hypothesis.4
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基因ID
- 25340
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NCBI登录号
- NM_006174
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UniProt
- Q63634
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途径
- Feeding Behaviour
抗原
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