NPTXR 抗体 (C-Term, Extracellular)
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Quick Overview for NPTXR 抗体 (C-Term, Extracellular) (ABIN7043370)
抗原
See all NPTXR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 162-176, C-Term, Extracellular
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原理
- A Rabbit Polyclonal Antibody to NPTXR (extracellular)
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat - identical, human - 14 out of 15 amino acid residues identical
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产品特性
- Anti-Neuronal Pentraxin Receptor (NPTXR)(extracellular) Antibody (ABIN7043370, ABIN7044746 and ABIN7044747) is a highly specific antibody directed against an extracellular epitope of the mouse NPTXR. The antibody can be used in western blot and immunohistochemistry. It has been designed to recognize NPTXR from mouse, rat and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)RGLQDAGPRRDTMAD, corresponding to amino acid residues 162 - 176 of mouse NPTXR
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亚型
- IgG
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anti-Neuronal Pentraxin Receptor (NPTXR) (AA 180-209) antibody
NPTXR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32555 unconjugated
anti-Neuronal Pentraxin Receptor (NPTXR) (AA 1-489) antibodyNPTXR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neuronal Pentraxin Receptor (NPTXR) (AA 162-176), (C-Term), (Extracellular) antibody (FITC)NPTXR 适用: 小鼠 FACS, LCI 宿主: 兔 Polyclonal FITC
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应用备注
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WB: 1:400
FC: 5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:1200
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236082)
Blocking Peptide: (ABIN7236082)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- NPTXR (Neuronal Pentraxin Receptor (NPTXR))
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别名
- NPTXR
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背景
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Synonyms: NPR, NPTXR
Description: Neuronal Pentraxin Receptor (NPTXR) belongs to the Pentraxin superfamily of proteins (NP) that is characterized by a pentraxin domain at the C-terminal end. It is the only pentraxin family member anchored to the cell membrane by a putative N-terminal transmembrane domain, as opposed to the other two family members, Neuronal Pentraxin1 (NP1) and Neuronal Pentraxin 2 (NP2) that are secreted proteins. NPs can form homo pentamers and hetero pentamers via their pentraxin domains 1.NPTXR was first identified as the receptor for the snake venom toxin taipoxin and was later found to bind to AMPARs at excitatory synapses and play important, roles in the activity-dependent regulation of neural circuits via this binding activity 1.Lately, the levels of NPTXR protein in cerebrospinal fluid has been identified as a novel potential biomarker of Alzheimer's disease progression and could have important utility in assessing treatment success in clinical trials 2. In addition, NPTXR was identified as a molecule required for gastric cancer metastasis 3.
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基因ID
- 73340
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NCBI登录号
- NM_014293
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UniProt
- Q99J85
抗原
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