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NMUR1 抗体 (Extracellular)

NMUR1 适用: 大鼠 WB, IHC, IF (cc), LCI 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7043365
发货至: 中国
  • 抗原 See all NMUR1 抗体
    NMUR1 (Neuromedin U Receptor 1 (NMUR1))
    抗原表位
    • 16
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 316-331, Extracellular
    适用
    • 42
    • 29
    • 26
    • 3
    • 3
    • 1
    大鼠
    宿主
    • 41
    • 1
    克隆类型
    • 42
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NMUR1 antibody is un-conjugated
    应用范围
    • 17
    • 13
    • 9
    • 6
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
    原理
    A Rabbit Polyclonal antibody to NMUR1 (extracellular)
    特异性
    Extracellular, 3rd loop.
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Human - 12 out of 16 amino acid residues identical, Mouse - 10 out of 16 amino acid residues identical
    产品特性
    A rabbit polyclonal antibody to NMUR1 (extracellular)
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)DRLMWSMVSHWTDGLR, corresponding to amino acid residues 316 - 331 of rat NMUR1

    亚型
    IgG
    Top Product
    Discover our top product NMUR1 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300

    Application Dilutions Western blot wb: 1:400-1:500

    说明

    Negative Control: BLP-NR071

    Blocking Peptide: BLP-NR071

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    NMUR1 (Neuromedin U Receptor 1 (NMUR1))
    别名
    NMUR1 (NMUR1 产品)
    背景
    Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66,Neuromedin U Receptor 1 (NMUR1) is one of the two receptors for the neuropeptide Neuromedin U (NMU). NMUR1 and the second receptor NMUR2 are members of the G protein coupled receptors (GPCRs) superfamily 1.NMU is a neuropeptide with potent activity on smooth muscles that is widely distributed in the gut and central nervous system. NMU interaction with one of its two receptors- NMU1R or NMU2R, mediates the stimulation of smooth muscles, increase of blood pressure, alteration of ion transport in the gut, control of local blood flow and regulation of adrenocortical function1-2.NMU1R is abundantly expressed in peripheral tissues including lung, GI tract, pancreatic islets, testis, adipose, immune tissues, and dorsal root ganglia2, and due to its diverse functions it is a very appealing drug and research candidate.

    Alternative names: Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66
    基因ID
    65276
    NCBI登录号
    NM_006056
    UniProt
    Q9JJI5
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