NMUR1 抗体 (Extracellular)
Quick Overview for NMUR1 抗体 (Extracellular) (ABIN7043365)
抗原
See all NMUR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 316-331, Extracellular
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原理
- A Rabbit Polyclonal antibody to NMUR1 (extracellular)
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特异性
- Extracellular, 3rd loop.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Human - 12 out of 16 amino acid residues identical, Mouse - 10 out of 16 amino acid residues identical
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产品特性
- A rabbit polyclonal antibody to NMUR1 (extracellular)
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)DRLMWSMVSHWTDGLR, corresponding to amino acid residues 316 - 331 of rat NMUR1
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亚型
- IgG
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anti-Neuromedin U Receptor 1 (NMUR1) (AA 360-426) antibody
NMUR1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuromedin U Receptor 1 (NMUR1) (N-Term) antibodyNMUR1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuromedin U Receptor 1 (NMUR1) (AA 31-80) antibodyNMUR1 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuromedin U Receptor 1 (NMUR1) (AA 31-80) antibody (AbBy Fluor® 488)NMUR1 适用: 人, 小鼠, 大鼠 FACS 宿主: 兔 Polyclonal AbBy Fluor® 488
anti-Neuromedin U Receptor 1 (NMUR1) (N-Term) antibodyNMUR1 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuromedin U Receptor 1 (NMUR1) (AA 2-68) antibodyNMUR1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:400-1:500
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说明
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Negative Control: (ABIN7236064)
Blocking Peptide: (ABIN7236064)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- NMUR1 (Neuromedin U Receptor 1 (NMUR1))
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别名
- NMUR1
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背景
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Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66,Neuromedin U Receptor 1 (NMUR1) is one of the two receptors for the neuropeptide Neuromedin U (NMU). NMUR1 and the second receptor NMUR2 are members of the G protein coupled receptors (GPCRs) superfamily 1.NMU is a neuropeptide with potent activity on smooth muscles that is widely distributed in the gut and central nervous system. NMU interaction with one of its two receptors- NMU1R or NMU2R, mediates the stimulation of smooth muscles, increase of blood pressure, alteration of ion transport in the gut, control of local blood flow and regulation of adrenocortical function1-2.NMU1R is abundantly expressed in peripheral tissues including lung, GI tract, pancreatic islets, testis, adipose, immune tissues, and dorsal root ganglia2, and due to its diverse functions it is a very appealing drug and research candidate.
Alternative names: Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66 -
基因ID
- 65276
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NCBI登录号
- NM_006056
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UniProt
- Q9JJI5
抗原
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