Neuroligin 1 抗体 (Extracellular)
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- 抗原 See all Neuroligin 1 (NLGN1) 抗体
- Neuroligin 1 (NLGN1)
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抗原表位
- AA 648-661, Extracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neuroligin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Live Cell Imaging (LCI), Immunochromatography (IC)
- 原理
- A Rabbit Polyclonal Antibody to Neuroligin 1
- 特异性
- Extracellular, N-terminus
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Mouse - identical, human - 13,14 amino acid residues identical
- 产品特性
- Anti-Neuroligin 1 (extracellular) Antibody is directed against an extracellular epitope of rat Neuroligin 1. Anti-Neuroligin 1 (extracellular) Antibody (ABIN7043361, ABIN7044680 and ABIN7044681)) can be used in western blot, immunohistochemistry and live cell imaging applications. It has been designed to recognize NLGN1 from rat, mouse and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KVPSTDITLRPTRK, corresponding to amino acid residues 648-661 of rat NLGN1
- 亚型
- IgG
- Top Product
- Discover our top product NLGN1 Primary Antibody
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anti-Neuroligin 1 (NLGN1) (AA 701-800) antibody
NLGN1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuroligin 1 (NLGN1) (AA 578-677) antibodyNLGN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neuroligin 1 (NLGN1) (AA 51-300) antibodyNLGN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibodyNLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 unconjugated
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (HRP)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 HRP
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (FITC)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 FITC
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (APC)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 APC
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (Atto 488)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 Atto 488
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (Biotin)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 Biotin
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (PE)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 PE
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:800
- 说明
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Negative Control: BLP-NR035
Blocking Peptide: BLP-NR035
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Neuroligin 1 (NLGN1)
- 别名
- NLGN1 (NLGN1 产品)
- 背景
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NLGN1, NL1,The NLGN1 gene encodes a member of a family of neuronal cell surface proteins. Neuroligins act as ligands for β-neurexins, cell adhesion proteins located presynaptically. Neuroligin and β-neurexin "shake hands," resulting in the connection between the two neurons and the production of a synapse. Neuroligin 1 may be involved in the formation and remodeling of central nervous system synapses1.Proteins of this family may also mediate signaling by recruiting and stabilizing key synaptic components. This is done by interacting with other postsynaptic proteins to localize neurotransmitter receptors and channels in the postsynaptic density as the cell matures1.Mutations in the neuroligin genes are implicated in autism and other cognitive disorders2.Neuroligins have been found to play a role in angiogenesis, specifically in human pheripheral tissues3.Neuroligins bind with the help of Ca2+ to the α-neurexin LNS (laminin, neurexin and sex hormone-binding globulin-like folding units) domains and to the β-neurexin LNS domain which then establishes a heterophilic trans-synaptic recognition code4. This binding results in a heterotetramer made up of a neuroligin-1 dimer and two neurexin-1 β monomers5.
Alternative names: Neuroligin 1, NLGN1, NL1 - 基因ID
- 116647
- NCBI登录号
- NM_014932
- UniProt
- Q62765
- 途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
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