MRGPRE 抗体 (3rd Intracellular Loop)
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Quick Overview for MRGPRE 抗体 (3rd Intracellular Loop) (ABIN7043319)
抗原
See all MRGPRE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 3rd Intracellular Loop, AA 197-209
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原理
- A Rabbit Polyclonal Antibody to MRGPRE Receptor
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse - identical, human - 10,13 amino acid residues identical
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产品特性
- Anti-MRGPRE Antibody (ABIN7043319, ABIN7044604 and ABIN7044605) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize MRGPRE from rat, human, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)RVERGPERHQPRG, corresponding to amino acid residues 197 - 209 of rat MRGPRE
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亚型
- IgG
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anti-MAS-Related GPR, Member E (MRGPRE) (C-Term) antibody
MRGPRE 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (Internal Region) antibodyMRGPRE 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (Internal Region) antibodyMRGPRE 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (Internal Region) antibodyMRGPRE 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (C-Term) antibodyMRGPRE 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (C-Term) antibodyMRGPRE 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (AA 171-220) antibodyMRGPRE 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (C-Term) antibodyMRGPRE 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:400
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235909)
Blocking Peptide: (ABIN7235909)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- MRGPRE (MAS-Related GPR, Member E (MRGPRE))
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别名
- MRGPRE
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背景
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Synonyms: Mas-related G-protein coupled receptor member E, GPCR MRGE, GPR167
Description: The Mas-related G protein-coupled receptors (MRGPRs), formerly called Mas-related genes (MRGs) includes nine members: MrgprA, B, C, D, E, F, G, H, and the primate-specific MRGPRX1,2.MRGPRE consist of only one receptor per species and is conserved in rodents and primates2. MRGPRE structure contains a Cys-Cys bridge from transmembrane domain (TM) 3, an "ionic-lock" known to inhibit activation and activity in some class A GPCRs1,2.Human and mouse MRGPRE is highly expressed in neurons of the brain and mast cells. Transcripts are also found in medium and large diameter neurons of human dorsal root ganglia (DRG) sections and in other areas of the central nervous system, including cerebral cortex, hippocampus, spinal cord, and cerebellum. MRGPRE was also found in human, mouse, and rat placenta tissue and in enteric neurons1,2.Mouse lacking the MRGPRE protein showed decreased nociceptive behavior and significant deficits in the induction of mechanical allodynia after chronic constriction injury2.
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基因ID
- 404660
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NCBI登录号
- NM_001039165
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UniProt
- Q7TN40
抗原
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