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- 抗原 See all MRGPRE 抗体
- MRGPRE (MAS-Related GPR, Member E (MRGPRE))
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抗原表位
- AA 197-209
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MRGPRE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to MRGPRE Receptor
- 特异性
- 3rd intracellular loop
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse - identical, human - 10,13 amino acid residues identical
- 产品特性
- Anti-MRGPRE Antibody (ABIN7043319, ABIN7044604 and ABIN7044605) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize MRGPRE from rat, human, and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RVERGPERHQPRG, corresponding to amino acid residues 197 - 209 of rat MRGPRE
- 亚型
- IgG
- Top Product
- Discover our top product MRGPRE Primary Antibody
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anti-MAS-Related GPR, Member E (MRGPRE) (C-Term) antibody
MRGPRE 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (Internal Region) antibodyMRGPRE 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (Internal Region) antibodyMRGPRE 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (Internal Region) antibodyMRGPRE 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (C-Term) antibodyMRGPRE 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (Internal Region) antibodyMRGPRE 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (C-Term) antibodyMRGPRE 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-MAS-Related GPR, Member E (MRGPRE) (AA 171-220) antibodyMRGPRE 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:400
- 说明
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Negative Control: (ABIN7235909)
Blocking Peptide: (ABIN7235909)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- MRGPRE (MAS-Related GPR, Member E (MRGPRE))
- 别名
- MRGPRE (MRGPRE 产品)
- 背景
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Mas-related G-protein coupled receptor member E, GPCR MRGE, GPR167,The Mas-related G protein-coupled receptors (MRGPRs), formerly called Mas-related genes (MRGs) includes nine members: MrgprA, B, C, D, E, F, G, H, and the primate-specific MRGPRX1,2.MRGPRE consist of only one receptor per species and is conserved in rodents and primates2. MRGPRE structure contains a Cys-Cys bridge from transmembrane domain (TM) 3, an "ionic-lock" known to inhibit activation and activity in some class A GPCRs1,2.Human and mouse MRGPRE is highly expressed in neurons of the brain and mast cells. Transcripts are also found in medium and large diameter neurons of human dorsal root ganglia (DRG) sections and in other areas of the central nervous system, including cerebral cortex, hippocampus, spinal cord, and cerebellum. MRGPRE was also found in human, mouse, and rat placenta tissue and in enteric neurons1,2.Mouse lacking the MRGPRE protein showed decreased nociceptive behavior and significant deficits in the induction of mechanical allodynia after chronic constriction injury2.
Alternative names: MRGPRE, Mas-related G-protein coupled receptor member E, GPCR MRGE, GPR167 - 基因ID
- 404660
- NCBI登录号
- NM_001039165
- UniProt
- Q7TN40
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