HCN2 抗体 (Intracellular)
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Quick Overview for HCN2 抗体 (Intracellular) (ABIN7043279)
抗原
See all HCN2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 147-161, Intracellular
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原理
- A Rabbit Polyclonal Antibody to HCN2 Channel
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特异性
- Intracellular, N-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,mouse - identical
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产品特性
- Anti-HCN2 Antibody (ABIN7043279, ABIN7044940 and ABIN7044941) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot, immunoprecipitation, immunohistochemistry, and immunocytochemistry applications. It has been designed to recognize HCN2 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)EEAGPAGEPRGSQAS, corresponding to amino acid residues 147-161 of human HCN2
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亚型
- IgG
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anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody
HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 unconjugated
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (HRP)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 HRP
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (FITC)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 FITC
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (Biotin)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 Biotin
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (PE)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 PE
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (APC)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 APC
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (PerCP)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 PerCP
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (Atto 488)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 Atto 488
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (Atto 594)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 Atto 594
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) (AA 761-863) antibody (Atto 390)HCN2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S71 Atto 390
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IP|IHC|ICC
Negative Control: (ABIN7235786)
Blocking Peptide: (ABIN7235786)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- HCN2 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2))
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别名
- HCN2
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背景
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Hyperpolarization-activated cyclic nucleotide-gated potassium channel 2, BCNG2, HAC-1,Hyperpolarization-activated cation currents (Ih) appear in the heart and the brain having crucial role in controlling electrical pacemaker activity, contributing to biological processes such as heartbeat, sleep-wake cycle and synaptic plasticity.1,2The Ih currents are generated by the hyperpolarization-activated cyclic nucleotide-gated channel family (HCN), which comprises four homologous members, named HCN1-4. Each HCN subunit consist of six transmembrane domains (TM), a pore region between TM5-TM6 and a binding domain to cyclic nucleotides (CNBD) in the cytoplasmic C-terminus.2The HCN subunits can form functional homomers and can also co-assemble into functional heteromers.2The channels are closely related to each other and share homology of about 60 % . However, they are diverging from each other in their cytoplasmic N- and the C-terminus. The channels HCN1-4 mainly differ from each other with regard to their speed of activation and the extent by which they are modulated by cAMP. HCN1 is the fastest channel, followed by HCN2, HCN3 and HCN4.2,3HCN2 is the most abundant neuronal channel and is found almost ubiquitously in the brain.3
Alternative names: HCN2, Hyperpolarization-activated cyclic nucleotide-gated potassium channel 2, BCNG2, HAC-1 -
基因ID
- 114244
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NCBI登录号
- NM_001194
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UniProt
- Q9UL51
抗原
-
