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GAP43 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects GAP43 in WB, IHC 和 IF. It exhibits reactivity toward 大鼠.
产品编号 ABIN7043263
发货至: 中国
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Quick Overview for GAP43 抗体 (C-Term) (ABIN7043263)

抗原

See all GAP43 抗体
GAP43 (Growth Associated Protein 43 (GAP43))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This GAP43 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 205-218, C-Term

    原理

    A Rabbit Polyclonal Antibody to GAP43

    交叉反应

    小鼠, 大鼠

    预测反应

    Mouse - identical, human - 13,14 amino acid residues identical

    产品特性

    Anti-GAP43 Antibody (ABIN7043263, ABIN7044662 and ABIN7044663) is a highly selective antibody directed against an epitope of rat Neuromodulin. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GAP43 from human, mouse, and rat samples.

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    (C)KPKESARQDEGKED, corresponding to amino acid residues 205-218 of rat GAP43

    亚型

    IgG
  • 应用备注

    WB: 1:400

    FC: The optimal concentration should be determined by the user

    ICC: The optimal concentration should be determined by the user

    IHC: 1:200

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7235735)

    Blocking Peptide: (ABIN7235735)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

    浓度

    0.8 mg/mL

    缓冲液

    PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    GAP43 (Growth Associated Protein 43 (GAP43))

    别名

    GAP43

    背景

    Synonyms: Axonal membrane protein GAP-43, Growth-associated protein 43, Neuromodulin, Neural phosphoprotein B-50

    Description: Growth associated protein 43 (GAP43) is a neuron specific phosphoprotein that plays an important role in the process of nerve growth, development, regeneration and axonal remodeling. GAP43 belongs to the calmodulin-binding protein family and is highly distributed in the presynaptic membrane1.GAP43 is expressed in developing neurons, especially in the growth cone. In mature neurons, GAP43 is detected in regenerating nerves. In brain injury, neurons exhibit sprouting of the lateral branches and responsive regeneration of the axon accompanied by increased expression of GAP43. GAP43 expression is used as an important tool for evaluating axon injury and the regenerative response in the mature central nervous system (CNS)1,2.

    基因ID

    29423

    NCBI登录号

    NM_002045

    UniProt

    P07936
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