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GAP43 抗体 (AA 205-218)

This anti-GAP43 antibody is a 兔 多克隆 antibody detecting GAP43 in WB, IHC 和 IF. Suitable for 大鼠.
产品编号 ABIN7043263
发货至: 中国

Quick Overview for GAP43 抗体 (AA 205-218) (ABIN7043263)

抗原

See all GAP43 抗体
GAP43 (Growth Associated Protein 43 (GAP43))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This GAP43 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 205-218

    原理

    A Rabbit Polyclonal Antibody to GAP43

    特异性

    C-terminus

    交叉反应

    小鼠, 大鼠

    预测反应

    Mouse - identical, human - 13,14 amino acid residues identical

    产品特性

    Anti-GAP43 Antibody (ABIN7043263, ABIN7044662 and ABIN7044663) is a highly selective antibody directed against an epitope of rat Neuromodulin. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GAP43 from human, mouse, and rat samples.

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)KPKESARQDEGKED, corresponding to amino acid residues 205-218 of rat GAP43

    亚型

    IgG
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200

    Application Dilutions Western blot wb: 1:400

    说明

    Negative Control: (ABIN7235735)

    Blocking Peptide: (ABIN7235735)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW).

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存条件

    4 °C,-20 °C

    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原

    GAP43 (Growth Associated Protein 43 (GAP43))

    别名

    GAP43

    背景

    Axonal membrane protein GAP-43, Growth-associated protein 43, Neuromodulin, Neural phosphoprotein B-50,Growth associated protein 43 (GAP43) is a neuron specific phosphoprotein that plays an important role in the process of nerve growth, development, regeneration and axonal remodeling. GAP43 belongs to the calmodulin-binding protein family and is highly distributed in the presynaptic membrane1.GAP43 is expressed in developing neurons, especially in the growth cone. In mature neurons, GAP43 is detected in regenerating nerves. In brain injury, neurons exhibit sprouting of the lateral branches and responsive regeneration of the axon accompanied by increased expression of GAP43. GAP43 expression is used as an important tool for evaluating axon injury and the regenerative response in the mature central nervous system (CNS)1,2.

    Alternative names: GAP43, Axonal membrane protein GAP-43, Growth-associated protein 43, Neuromodulin, Neural phosphoprotein B-50

    基因ID

    29423

    NCBI登录号

    NM_002045

    UniProt

    P07936
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