GNRHR 抗体 (Extracellular)
Quick Overview for GNRHR 抗体 (Extracellular) (ABIN7043262)
抗原
See all GNRHR 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 3-13, Extracellular
-
原理
- A Rabbit Polyclonal Antibody to GnRH Receptor
-
特异性
- Extracellular, N-terminus
-
交叉反应
- 小鼠, 大鼠
-
交叉反应 （详细）
- Not recommended for use with human samples.
-
预测反应
- Mouse - identical
-
产品特性
- Anti-GnRH Receptor (extracellular) Antibody (ABIN7043262 and ABIN7044416) is a highly specific antibody directed against an epitope of rat GnRHR. The antibody can be used in western blot and immunohistochemistry applications. The antibody recognizes an extracellular epitope, and can potentially be used for detecting the protein in living cells. It has been designed to recognize GnRHR from mouse and rat samples. It is not suited to recognize GnRHR from human samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: (C)NNASLEQDQNH, corresponding to amino acid residues 3-13 of rat GnRHR
-
亚型
- IgG
-
-
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (AA 201-328) antibody
GNRHR 适用: 人, 大鼠 WB, ELISA, IHC (p), IHC (fro), ICC, IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) antibodyGNRHR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) antibodyGNRHR 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (Internal Region) antibodyVerified GNRHR 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (N-Term) antibodyGNRHR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
-
说明
-
Cited Application: IHC
Negative Control: (ABIN7235732)
Blocking Peptide: (ABIN7235732)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
-
别名
- GnRHR
-
背景
-
Gonadotropin-releasing hormone receptor, GnRHR, Leutinizing hormone releasing hormone receptor, LHRHR, Luliberin receptor,Gonadotropin-releasing hormone (GnRH) or Luteinizing hormone releasing hormone (LHRH) is a decapeptide synthesized and released from neurons in the hypothalamus and stimulates the synthesis and release of gonadotropin hormone (or luteinizing hormone) and follicle stimulating hormone from the pituitary gland1. GnRH is expressed as various variants, and most vertebrates express more than one form of GnRH1-3.GnRH and its variants bind and activate GnRH receptor (GnRHR), a member of the G-protein coupled receptor (GPCR) superfamily. Three forms of the receptor have been identified in vertebrates (types I, II and III). Like all members, GnRHR has seven transmembrane domains and an extracellular N-terminus and an intracellular C-terminal tail. The receptor also has a number of glycosylation sites in its extracellular loops. In addition, the C-terminal tail is unusually short and lacks consensus sites known to undergo post-translational modifications like phosphorylation. In consequence, this affects the receptor's desensitization and internalization4.Expression of GnRHR is detected in the gonadotrope and various tissues like the breast, gonads, prostate and uterus4,5.
Alternative names: GnRH Receptor, Gonadotropin-releasing hormone receptor, GnRHR, Leutinizing hormone releasing hormone receptor, LHRHR, Luliberin receptor -
基因ID
- 81668
-
NCBI登录号
- NM_001083111
-
UniProt
- P30969
抗原
-
