GLRA3 抗体 (2nd Cytoplasmic Loop)
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Quick Overview for GLRA3 抗体 (2nd Cytoplasmic Loop) (ABIN7043258)
抗原
See all GLRA3 (GLRa3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 2nd Cytoplasmic Loop, AA 355-368
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原理
- A Rabbit Polyclonal Antibody to Glycine Receptor α3
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,human - identical
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产品特性
- Anti-Glycine Receptor alpha3 Antibody is directed against an epitope of the rat glycine receptor α3. Anti-Glycine Receptor α3 Antibody (ABIN7043258 and ABIN7044396) can be used in western blot and immunohistochemistry applications. It has been designed to recognize GlyRα3 from rat, mouse and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)KNKTEAFALEKFYR, corresponding to amino acid residues 355-368 of rat GlyRalpha3
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亚型
- IgG
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:300
IP: The optimal concentration should be determined by the user
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说明
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Cited Application: IHC
Negative Control: (ABIN7235717)
Blocking Peptide: (ABIN7235717)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- GLRA3 (GLRa3) (Glycine Receptor, alpha 3 (GLRa3))
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别名
- GLRA3
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背景
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Synonyms: Glycine receptor subunit alpha-3, GLRA3, GlyRα3
Description: Glycine is a major neurotransmitter in the mammalian central nervous system.1 The glycine receptor is a ligand gated Cl- channel, mediating synaptic inhibition in the spinal cord, retina and regions of the brain.2The glycine receptor is a pentamer consisting of α and β subunits. To date there are four known α-subunit isoforms (α1-α4) encoded by different genes.2-4 In humans, two alternative splice variants of the glycine receptor α3 have been described: α3L and α3K, where the α3L splice variant bears an additional segment of 15 amino acids within the long cytoplasmic TM3-4 loop. These variants differ in their desensitization kinetics.3
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基因ID
- 114516
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NCBI登录号
- NM_001042543
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UniProt
- P24524
抗原
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