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GLRA3 抗体 (AA 355-368)

This 兔 多克隆 anti-GLRA3 antibody specifically detects GLRA3 in WB 和 IHC. The antibody is reactive with 大鼠 samples.
产品编号 ABIN7043258
发货至: 中国
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Quick Overview for GLRA3 抗体 (AA 355-368) (ABIN7043258)

抗原

See all GLRA3 (GLRa3) 抗体
GLRA3 (GLRa3) (Glycine Receptor, alpha 3 (GLRa3))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This GLRA3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 355-368

    原理

    A Rabbit Polyclonal Antibody to Glycine Receptor α3

    特异性

    2nd intracellular loop

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Mouse,human - identical

    产品特性

    Anti-Glycine Receptor alpha3 Antibody is directed against an epitope of the rat glycine receptor α3. Anti-Glycine Receptor α3 Antibody (ABIN7043258 and ABIN7044396) can be used in western blot and immunohistochemistry applications. It has been designed to recognize GlyRα3 from rat, mouse and human samples.

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)KNKTEAFALEKFYR, corresponding to amino acid residues 355-368 of rat GlyRalpha3

    亚型

    IgG
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300

    Application Dilutions Western blot wb: 1:200

    说明

    Cited Application: IHC

    Negative Control: (ABIN7235717)

    Blocking Peptide: (ABIN7235717)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW).

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存条件

    4 °C,-20 °C

    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原

    GLRA3 (GLRa3) (Glycine Receptor, alpha 3 (GLRa3))

    别名

    GLRA3

    背景

    Glycine receptor subunit alpha-3, GLRA3, GlyRα3,Glycine is a major neurotransmitter in the mammalian central nervous system.1 The glycine receptor is a ligand gated Cl- channel, mediating synaptic inhibition in the spinal cord, retina and regions of the brain.2The glycine receptor is a pentamer consisting of α and β subunits. To date there are four known α-subunit isoforms (α1-α4) encoded by different genes.2-4 In humans, two alternative splice variants of the glycine receptor α3 have been described: α3L and α3K, where the α3L splice variant bears an additional segment of 15 amino acids within the long cytoplasmic TM3-4 loop. These variants differ in their desensitization kinetics.3

    Alternative names: Glycine Receptor alpha3, Glycine receptor subunit alpha-3, GLRA3, GlyRalpha3

    基因ID

    114516

    NCBI登录号

    NM_001042543

    UniProt

    P24524
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