GRIP1 抗体 (C-Term, Intracellular)
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Quick Overview for GRIP1 抗体 (C-Term, Intracellular) (ABIN7043227)
抗原
See all GRIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 963-977, C-Term, Intracellular
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原理
- A Rabbit Polyclonal Antibody to GRIP1
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,human - identical
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产品特性
- Anti-GRIP1 Antibody (ABIN7043227, ABIN7045158 and ABIN7045159) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize GRIP1 from human, mouse, and rat samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)RKSVTLRKMKQEIKE, corresponding to amino acid residues 963-977 of rat GRIP1
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亚型
- IgG
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anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 851-950) antibody
GRIP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A9 unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (Internal Region) antibodyGRIP1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (C-Term) antibodyGRIP1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 犬, 马, 斑马鱼, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 1-100) antibodyGRIP1 适用: 小鼠 WB, ICC, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 874-1073) antibodyGRIP1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 851-950) antibodyGRIP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (N-Term) antibodyGRIP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (N-Term) antibodyGRIP1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 1-190) antibodyGRIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 950-999) antibodyGRIP1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 犬, 斑马鱼, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235622)
Blocking Peptide: (ABIN7235622)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))
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别名
- GRIP1
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背景
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Synonyms: Glutamate receptor interacting protein 1
Description: GRIP1 (glutamate receptor interacting protein 1) is a neuron-enriched scaffolding protein that plays an important role in regulating synaptic trafficking, synaptic strength and synaptic organization and transmission of AMPA receptor 2 and 3 (GluA2/3) 1,2. GRIP1 structure contains 7 PDZ domains responsible for protein-protein interactions. GRIP1 forms homodimers that can bind and simultaneously organize and assemble protein complexes via PDZ domains1,2.GRIP1 is abundantly expressed in glutamatergic and GABAergic synapses. In addition, GRIP1 expression can be found in muscle cells and in the epidermis1,3. Studies on GRIP1 knockout mice have revealed multi-organ developmental abnormalities. These mice die due to hemorrhage and hypovolemia in the embryonic or early post-natal period2.Mutations in GRIP1 protein resulting in a gain-of-function phenotype are linked to autism, while neuronal-specific loss-of-function mice have prosocial behavior. Other point mutations have been associated with schizophrenia and congenital kidney disease2,3.
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基因ID
- 84016
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NCBI登录号
- NM_001178074
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UniProt
- P97879
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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