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GRIP1 抗体 (Intracellular)

This anti-GRIP1 antibody is a 兔多克隆 antibody detecting GRIP1 in WB. Suitable for 大鼠.

$Western blot analysis of rat brain synaptosomal fraction: - 1. (GRIP1 抗体 (Intracellular))$ WB

Western blot analysis of mouse brain lysate: - 1. (GRIP1 抗体 (Intracellular))

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产品编号 ABIN7043227

发货至: 中国

Quick Overview for GRIP1 抗体 (Intracellular) (ABIN7043227)

抗原

See all GRIP1 抗体

GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

适用

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大鼠

宿主

兔

克隆类型

多克隆

标记

30
3
2
1
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1

This GRIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

Discover our top product GRIP1 Primary Antibody

抗原表位
15

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1
AA 963-977, Intracellular

原理

A Rabbit Polyclonal Antibody to GRIP1

特异性

Intracellular, C-terminus

交叉反应

人, 小鼠, 大鼠

预测反应

Mouse,human - identical

产品特性

Anti-GRIP1 Antibody (ABIN7043227, ABIN7045158 and ABIN7045159) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize GRIP1 from human, mouse, and rat samples.

纯化方法

Affinity purified on immobilized antigen.

免疫原

Immunogen: Synthetic peptide
Immunogen Sequence: (C)RKSVTLRKMKQEIKE, corresponding to amino acid residues 963-977 of rat GRIP1

亚型

IgG
anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 851-950) antibody
GRIP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A9 unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (Internal Region) antibody
GRIP1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (C-Term) antibody
GRIP1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 犬, 马, 斑马鱼, Cow WB 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 1-100) antibody
GRIP1 适用: 小鼠 WB, ICC, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 874-1073) antibody
GRIP1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 851-950) antibody
GRIP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (N-Term) antibody
GRIP1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 950-999) antibody
GRIP1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 犬, 斑马鱼, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 1-190) antibody
GRIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor Interacting Protein 1 (GRIP1) (AA 700-950) antibody
GRIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200

说明

Negative Control: (ABIN7235622)
Blocking Peptide: (ABIN7235622)

限制

仅限研究用
状态

Lyophilized

溶解方式

0.2 mL double distilled water (DDW).

浓度

1 mg/mL

缓冲液

PBS pH 7.4

储存条件

4 °C,-20 °C

储存方法

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
抗原

GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

别名

GRIP1

背景

Glutamate receptor interacting protein 1,GRIP1 (glutamate receptor interacting protein 1) is a neuron-enriched scaffolding protein that plays an important role in regulating synaptic trafficking, synaptic strength and synaptic organization and transmission of AMPA receptor 2 and 3 (GluA2/3) 1,2. GRIP1 structure contains 7 PDZ domains responsible for protein-protein interactions. GRIP1 forms homodimers that can bind and simultaneously organize and assemble protein complexes via PDZ domains1,2.GRIP1 is abundantly expressed in glutamatergic and GABAergic synapses. In addition, GRIP1 expression can be found in muscle cells and in the epidermis1,3. Studies on GRIP1 knockout mice have revealed multi-organ developmental abnormalities. These mice die due to hemorrhage and hypovolemia in the embryonic or early post-natal period2.Mutations in GRIP1 protein resulting in a gain-of-function phenotype are linked to autism, while neuronal-specific loss-of-function mice have prosocial behavior. Other point mutations have been associated with schizophrenia and congenital kidney disease2,3.

Alternative names: GRIP1, Glutamate receptor interacting protein 1

基因ID

84016

NCBI登录号

NM_001178074

UniProt

P97879

途径

Intracellular Steroid Hormone Receptor Signaling Pathway

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