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- 抗原 See all GLP2R 抗体
- GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))
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抗原表位
- AA 241-255, Extracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLP2R antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to Glucagon-like Peptide 2 Receptor
- 特异性
- 1st extracellular loop
- 预测反应
- Mouse,human - 13,15 amino acid residues identical
- 产品特性
- Anti-GLP2R (extracellular) Antibody (ABIN7043221, ABIN7044408 and ABIN7044409)) is a highly specific antibody directed against an epitpe of the rat glucagon-like peptide 2 receptor. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GLP2R from human, rat, and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KRPDDESGWMSYLSE, corresponding to amino acid residues 241-255 of rat GLP2R
- 亚型
- IgG
- Top Product
- Discover our top product GLP2R Primary Antibody
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anti-Glucagon-Like Peptide 2 Receptor (GLP2R) antibody
GLP2R 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) antibodyGLP2R 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (C-Term) antibodyGLP2R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (AA 1-180) antibodyGLP2R 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (N-Term) antibodyGLP2R 适用: 人, 猴, 豚鼠 WB, IHC, IHC (p), IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (AA 69-178) antibodyGLP2R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (AA 69-178) antibodyGLP2R 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (AA 1-180) antibodyGLP2R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (N-Term) antibodyGLP2R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (N-Term) antibodyGLP2R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
- 说明
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Cited Application: IHC
Negative Control: BLP-GR022
Blocking Peptide: BLP-GR022
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))
- 别名
- GLP2R (GLP2R 产品)
- 背景
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Glucagon-like peptide 2 receptor, GLP-2 receptor,Glucagon like peptide-2 (GLP-2) is a 33 amino acid peptide secreted following food consumption. It is cleaved by dipeptidyl peptidase IV thereby yielding a very short half life. GLP-2 imposes most of its effect on intestinal epithelial cells where it is also be used as a therapeutic drug for gastrointestinal injuries1-3.The many actions of GLP-2 include cellular proliferation of intestinal epithelial cells, the increase of amino acid and lipid absorption and increase of digestive enzyme activity of the epithelial brush border cells1.The GLP-2 cellular and physiological effects are primarily exerted through the glucagon-like peptide-2 receptor (GLP-2R), a member of the G-protein coupled receptor superfamily. The receptor can couple either Gs or Gi G-proteins1. However, when heterologously expressed, the receptor can stimulate the synthesis of cAMP3.Expression of GLP-2R is strongly detected in the central nervous system and the gastrointestinal tract, although its expression in this area remains controversial as some species express the receptor in different regions than others. It is also slightly detected in the lungs, cervix and vagal afferents1.
Alternative names: GLP2R, Glucagon-like peptide 2 receptor, GLP2 receptor - 基因ID
- 60432
- NCBI登录号
- NM_004246
- UniProt
- Q9Z0W0
- 途径
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour
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