GIPC1 抗体 (Intracellular)
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Quick Overview for GIPC1 抗体 (Intracellular) (ABIN7043215)
抗原
See all GIPC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-24, Intracellular
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原理
- A Rabbit Polyclonal Antibody to GIPC1
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特异性
- Intracellular, N-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,mouse - 14,15 amino acid residues identical
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产品特性
- Anti-GIPC1 Antibody (ABIN7043215, ABIN7045188 and ABIN7045189) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GIPC1 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KAPPLVENEEAEPGR, corresponding to amino acid residues 10-24 of human GIPC1
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亚型
- IgG
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anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) (AA 7-74) antibody
GIPC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) antibodyGIPC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) (C-Term) antibodyVerified GIPC1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) (AA 61-158) antibodyGIPC1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) (AA 40-89) antibodyGIPC1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, Bat, Hamster, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) antibodyKD Validated GIPC1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB6645 unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) (C-Term) antibodyGIPC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) (AA 101-160) antibodyGIPC1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) (AA 1-333) antibodyGIPC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) antibodyGIPC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:400
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说明
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Negative Control: (ABIN7235592)
Blocking Peptide: (ABIN7235592)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))
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别名
- GIPC1
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背景
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PDZ domain-containing protein GIPC1, GIPC, GAIP C-terminus-interacting protein, RGS-GAIP-interacting protein, Synectin, NIP, TIP-2,GIPC1 belongs to a family of evolutionarily conserved adaptor proteins responsible for the trafficking of numerous transmembrane proteins via endocytosis. Members of GIPC (GAIP interacting protein, C-terminus) have three main domains responsible for protein interactions, a PDZ domain which is flanked by GH1 and GH2 domains. GH1 domain is responsible for the dimerization of the protein, while GH2 is important for the interaction of GIPC1 with MYO6, a retrograde motor protein involved in protein trafficking. The PDZ domain of GIPC1 is responsible for the protein to interact with numerous proteins, namely β1-adrenoceptor, D2 dopamine receptor, GLUT1, TrkA receptor just to name a few. The zebrafish ortholog also interacts with Neuropilin-21,2.GIPC1 expression is upregulated in breast, ovarian and pancreas cancers2.
Alternative names: GIPC1, PDZ domain-containing protein GIPC1, GIPC, GAIP C-terminus-interacting protein, RGS-GAIP-interacting protein, Synectin, NIP, TIP-2 -
基因ID
- 10755
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NCBI登录号
- NM_005716
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UniProt
- O14908
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途径
- Dicarboxylic Acid Transport
抗原
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