GALR2 抗体 (AA 223-235)
Quick Overview for GALR2 抗体 (AA 223-235) (ABIN7043181)
抗原
See all GALR2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 223-235
-
原理
- A Rabbit Polyclonal Antibody to Galanin Receptor Type 2
-
特异性
- 3rd intracellular loop
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Rat - identical, human - 11,13 amino acid residues identical
-
产品特性
- Anti-GALR2 Antibody is directed against an epitope of the mouse Galanin receptor 2. Anti-GALR2 Antibody (ABIN7043181, ABIN7044398 and ABIN7044399) can be used in western blot and immunohistochemistry applications. It has been designed to recognize GALR2 from mouse, rat and human samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: (C)GSGSQRAKRKVTR, corresponding to amino acid residues 223-235 of mouse Galanin receptor type 2
-
亚型
- IgG
-
-
anti-Galanin Receptor 2 (GALR2) (AA 51-150) antibody
GALR2 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Transmembrane Domain) antibodyGALR2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (C-Term) antibodyGALR2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 282-387) antibodyGALR2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) antibodyGALR2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Internal Region) antibodyVerified GALR2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 50-150) antibodyGALR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
-
说明
-
Negative Control: (ABIN7235477)
Blocking Peptide: (ABIN7235477)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW).
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- GALR2 (Galanin Receptor 2 (GALR2))
-
别名
- GALR2
-
背景
-
Galanin receptor type 2, GALNR2, GAL2R,Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known receptors, the Galanin receptor type 1 (GALR1), Galanin receptor type 2 (GALR2) and Galanin receptor type 3 (GALR3). The Galanin receptors belong to the G-protein coupled receptor superfamily.1-4GALR2 is widely expressed in the brain (with highest levels of mRNA found in the hypothalamus, hippocampus, amygdala and pyriform cortex) and in peripheral tissues such as the small intestine, heart, kidney, and liver. High levels of GALR2 expression were also found in rat dorsal root ganglia.1GALR2 activation increases inositol phosphate hydrolysis, mediates the release of Ca2+ into the cytoplasm from intracellular stores, and opens Ca2+-dependent chloride channels in a PTX-resistant manner, indicating that GALR2 couples to Gq/11 proteins.5
Alternative names: GALR2, Galanin receptor type 2, GALNR2, GAL2R -
基因ID
- 14428
-
NCBI登录号
- NM_003857
-
UniProt
- O88854
-
途径
- cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
抗原
-
