GPR83 抗体 (Extracellular, N-Term)
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Quick Overview for GPR83 抗体 (Extracellular, N-Term) (ABIN7043174)
抗原
See all GPR83 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-71, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to GPR83
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Human,rat - identical
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产品特性
- Anti-GPR83 (extracellular) Antibody (ABIN7043174, ABIN7044445 and ABIN7044446) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot and indirect live cell flow cytometry applications. It has been designed to recognize GPR83 from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)RRYGAESQNPTVK, corresponding to amino acid residues 59 - 71 of mouse GPR83
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亚型
- IgG
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anti-G Protein-Coupled Receptor 83 (GPR83) (AA 200-250) antibody
GPR83 适用: 人, 小鼠, 大鼠, Cow, 猴, 犬, 小鸡, 非洲爪蟾 WB, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) antibodyGPR83 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (AA 349-423) antibodyGPR83 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (Extracellular Domain) antibodyGPR83 适用: 人, Pig, Cow, 猴, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (Cytoplasmic Domain) antibodyGPR83 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) antibodyGPR83 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (AA 59-71) antibodyVerified GPR83 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (AA 17-30) antibodyVerified GPR83 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (N-Term) antibodyGPR83 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (N-Term) antibodyGPR83 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:400
FC: 5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:3000
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235450)
Blocking Peptide: (ABIN7235450)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- GPR83 (G Protein-Coupled Receptor 83 (GPR83))
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别名
- GPR83
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背景
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Synonyms: G-protein coupled receptor 83, G-protein coupled receptor 72, GPR72, Glucocorticoid induced receptor, GIR
Description: GPR83 (JP05, GIR, GPR72) is a G-protein coupled receptor (GPCR) highly expressed in the brain, spleen and thymus, suggesting that this receptor may be targeted to treat neurological and immune disorders1.GPCR is a family of receptors responsible for initiation of a myriad of intracellular signaling cascades, these receptors are characterized by an extracellular N-terminus, intracellular C-terminal tail, and seven membrane-spanning α-helices (TM-1 to TM-7)2.In the brain GPR83 is expressed in the hippocampus, amygdala, prefrontal cortex, and in various hypothalamic nuclei where it may play a significant role in learning memory, reward, emotional behaviors, and stress regulation3. GPR83 is also expressed in regulatory T cells (Tregs) and it could potentially be used as a specific marker used to identify natural Tregs4.GPR83 was considered as an "orphan" GPCR. Recently, PEN, a neuropeptide was identified as its endogenous ligand1.
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基因ID
- 14608
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NCBI登录号
- NM_016540
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UniProt
- P30731
抗原
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