GPR83 抗体 (Extracellular)
-
- 抗原 See all GPR83 抗体
- GPR83 (G Protein-Coupled Receptor 83 (GPR83))
-
抗原表位
- AA 59-71, Extracellular
-
适用
- 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GPR83 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal Antibody to GPR83
- 特异性
- Extracellular, N-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Human,rat - identical
- 产品特性
- Anti-GPR83 (extracellular) Antibody (ABIN7043174, ABIN7044445 and ABIN7044446)) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot and indirect live cell flow cytometry applications. It has been designed to recognize GPR83 from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: (C)RRYGAESQNPTVK, corresponding to amino acid residues 59 - 71 of mouse GPR83
- 亚型
- IgG
- Top Product
- Discover our top product GPR83 Primary Antibody
-
anti-G Protein-Coupled Receptor 83 (GPR83) (AA 200-250) antibody
GPR83 适用: 人, 小鼠, 大鼠, Cow, 猴, 犬, 小鸡, 非洲爪蟾 WB, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (AA 349-423) antibodyGPR83 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) antibodyGPR83 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (Cytoplasmic Domain) antibodyGPR83 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (Extracellular Domain) antibodyGPR83 适用: 人, Pig, Cow, 猴, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (C-Term) antibodyGPR83 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) antibodyGPR83 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (C-Term) antibodyGPR83 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (N-Term) antibodyGPR83 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 83 (GPR83) (N-Term) antibodyGPR83 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:3000
Application Dilutions Western blot wb: 1:400
- 说明
-
Negative Control: BLP-GR053
Blocking Peptide: BLP-GR053
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
- 抗原
- GPR83 (G Protein-Coupled Receptor 83 (GPR83))
- 别名
- GPR83 (GPR83 产品)
- 背景
-
G-protein coupled receptor 83, G-protein coupled receptor 72, GPR72, Glucocorticoid induced receptor, GIR,GPR83 (JP05, GIR, GPR72) is a G-protein coupled receptor (GPCR) highly expressed in the brain, spleen and thymus, suggesting that this receptor may be targeted to treat neurological and immune disorders1.GPCR is a family of receptors responsible for initiation of a myriad of intracellular signaling cascades, these receptors are characterized by an extracellular N-terminus, intracellular C-terminal tail, and seven membrane-spanning α-helices (TM-1 to TM-7)2.In the brain GPR83 is expressed in the hippocampus, amygdala, prefrontal cortex, and in various hypothalamic nuclei where it may play a significant role in learning memory, reward, emotional behaviors, and stress regulation3. GPR83 is also expressed in regulatory T cells (Tregs) and it could potentially be used as a specific marker used to identify natural Tregs4.GPR83 was considered as an "orphan" GPCR. Recently, PEN, a neuropeptide was identified as its endogenous ligand1.
Alternative names: G-protein coupled receptor 83, G-protein coupled receptor 72, GPR72, Glucocorticoid induced receptor, GIR - 基因ID
- 14608
- NCBI登录号
- NM_016540
- UniProt
- P30731
-
