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GPR83 抗体 (Extracellular)

Name: GPR83 抗体 (Extracellular)
SKU: ABIN7043174
Availability: OutOfStock

This anti-GPR83 antibody is a 兔多克隆 antibody detecting GPR83 in WB, IHC, FACS 和 LCI. Suitable for 小鼠.

Western blot analysis of human Jurkat T-cell leukemia cell line lysate: - 1. (GPR83 抗体 (Extracellular))

Expression of GPR83 in mouse hippocampus and cortex - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-GPR83 (extracellular) Antibody (ABIN7043174, ABIN7044445 and ABIN7044446), (1:3000), followed by goat anti-rabbit-AlexaFluor-488. (GPR83 抗体 (Extracellular))

IHC

Cell surface detection of GPR83 in live intact human Jurkat T-cell leukemia cells: (black line) Cells. (GPR83 抗体 (Extracellular))

FACS

Western blot analysis of mouse brain membranes (lanes 1 and 3) and rat brain membranes (lanes 2 and 4): - 1, 2. (GPR83 抗体 (Extracellular))

4 images

产品编号 ABIN7043174

发货至: 中国

Quick Overview for GPR83 抗体 (Extracellular) (ABIN7043174)

抗原

See all GPR83 抗体

GPR83 (G Protein-Coupled Receptor 83 (GPR83))

适用

小鼠

宿主

兔

克隆类型

多克隆

标记

This GPR83 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Discover our top product GPR83 Primary Antibody

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AA 59-71, Extracellular

原理

A Rabbit Polyclonal Antibody to GPR83

特异性

Extracellular, N-terminus

交叉反应

人, 小鼠, 大鼠

预测反应

Human,rat - identical

产品特性

Anti-GPR83 (extracellular) Antibody (ABIN7043174, ABIN7044445 and ABIN7044446) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot and indirect live cell flow cytometry applications. It has been designed to recognize GPR83 from rat, mouse, and human samples.

纯化方法

Affinity purified on immobilized antigen.

免疫原

Immunogen: Synthetic peptide
Immunogen Sequence: (C)RRYGAESQNPTVK, corresponding to amino acid residues 59 - 71 of mouse GPR83

亚型

IgG
anti-G Protein-Coupled Receptor 83 (GPR83) (AA 200-250) antibody
GPR83 适用: 人, 小鼠, 大鼠, Cow, 猴, 犬, 小鸡, 非洲爪蟾 WB, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) (AA 349-423) antibody
GPR83 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) (Cytoplasmic Domain) antibody
GPR83 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) (Extracellular Domain) antibody
GPR83 适用: 人, Pig, Cow, 猴, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) antibody
GPR83 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) (C-Term) antibody
GPR83 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) antibody
GPR83 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) (AA 17-30) antibody
Verified GPR83 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) (AA 59-71) antibody
Verified GPR83 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-G Protein-Coupled Receptor 83 (GPR83) (N-Term) antibody
GPR83 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:3000
Application Dilutions Western blot wb: 1:400

说明

Negative Control: (ABIN7235450)
Blocking Peptide: (ABIN7235450)

限制

仅限研究用
状态

Lyophilized

溶解方式

Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

浓度

1 mg/mL

缓冲液

PBS pH 7.4

储存条件

4 °C,-20 °C

储存方法

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
抗原

GPR83 (G Protein-Coupled Receptor 83 (GPR83))

别名

GPR83

背景

G-protein coupled receptor 83, G-protein coupled receptor 72, GPR72, Glucocorticoid induced receptor, GIR,GPR83 (JP05, GIR, GPR72) is a G-protein coupled receptor (GPCR) highly expressed in the brain, spleen and thymus, suggesting that this receptor may be targeted to treat neurological and immune disorders1.GPCR is a family of receptors responsible for initiation of a myriad of intracellular signaling cascades, these receptors are characterized by an extracellular N-terminus, intracellular C-terminal tail, and seven membrane-spanning α-helices (TM-1 to TM-7)2.In the brain GPR83 is expressed in the hippocampus, amygdala, prefrontal cortex, and in various hypothalamic nuclei where it may play a significant role in learning memory, reward, emotional behaviors, and stress regulation3. GPR83 is also expressed in regulatory T cells (Tregs) and it could potentially be used as a specific marker used to identify natural Tregs4.GPR83 was considered as an "orphan" GPCR. Recently, PEN, a neuropeptide was identified as its endogenous ligand1.

Alternative names: G-protein coupled receptor 83, G-protein coupled receptor 72, GPR72, Glucocorticoid induced receptor, GIR

基因ID

14608

NCBI登录号

NM_016540

UniProt

P30731