GPR77 抗体 (Extracellular)
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- 抗原 See all GPR77 抗体
- GPR77 (G Protein-Coupled Receptor 77 (GPR77))
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抗原表位
- AA 4-18, Extracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPR77 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal Antibody to C5a Anaphylatoxin Receptor 2
- 特异性
- Extracellular, N-terminus
- 交叉反应 （详细）
- Will not recognize C5a Anaphylatoxin Chemotactic Receptor 2 from rat or mouse samples.
- 预测反应
- Human only
- 产品特性
- Anti-Human C5aR2 (extracellular) Antibody (ABIN7043172, ABIN7043928 and ABIN7043929) is a highly specific antibody directed against an epitope of human C5a anaphylatoxin receptor 2 (C5aR2, C5L2). The antibody can be used in western blot analysis. It recognizes an extracellular epitope and is likely to detect the receptor in living cells. It has been designed to recognize C5L2 from human samples only.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)DSVSYEYGDYSDLSD, corresponding to amino acid residues 4-18 of human C5a anaphylatoxin chemotactic receptor 2
- 亚型
- IgG
- Top Product
- Discover our top product GPR77 Primary Antibody
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anti-G Protein-Coupled Receptor 77 (GPR77) (AA 179-193), (Extracellular) antibody
GPR77 适用: 小鼠 WB, IF (cc), IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 77 (GPR77) (AA 2-19) antibodyGPR77 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 77 (GPR77) (Extracellular Domain) antibodyGPR77 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 77 (GPR77) (AA 1-337) antibodyGPR77 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 77 (GPR77) (C-Term) antibodyGPR77 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 77 (GPR77) antibodyGPR77 适用: 人, Non-Human Primate WB, FACS 宿主: 小鼠 Monoclonal 1D9-M12 unconjugated
anti-G Protein-Coupled Receptor 77 (GPR77) antibody (PE)GPR77 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 1D9-M12 PE
anti-G Protein-Coupled Receptor 77 (GPR77) (C-Term) antibodyGPR77 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 77 (GPR77) antibodyGPR77 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
anti-G Protein-Coupled Receptor 77 (GPR77) (AA 258-337) antibodyGPR77 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:400
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- GPR77 (G Protein-Coupled Receptor 77 (GPR77))
- 别名
- C5AR2 (GPR77 产品)
- 背景
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C5a anaphylatoxin chemotactic receptor 2, C5a anaphylatoxin receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5L2, GPR77,Complement fragment C5a is a pro-inflammatory polypeptide produced during activation of the complement cascade of serum proteins in response to foreign surfaces such as microorganisms and tissue damaged by physical or chemical injury. C5a binds to at least two seven-transmembrane domain receptors, C5aR (C5R1, CD88) and C5L2 (gpr77).Expression of C5L2 (C5a Anaphylatoxin Receptor 2) can be found in various tissues and cells such as astrocytes, neutrophils/macrophages, mast cells, immature dendritic cells, as well as in the brain, lung, heart, kidney, liver, ovary or testis.The C5L2 receptor is a G-protein coupled receptor clustered with other chemoattractant receptors, such as type-II angiotensin-II receptor, bradykinin receptors, the formyl peptide receptor family, ChemR23 and several orphan GPCRs. A small number of single-nucleotide polymorphisms (SNP) have been found in the receptor gene. C5L2 has two synonymous SNPs at 614G/A and 860C, however there are no known associations between these SNPs and human disease.Although C5L2 has the conventional structure of a GPCR, studies have shown that C5L2 does not couple to G proteins owing to the lack of a highly conserved Asp-Arg-Tyr motif, found in the third TM domain1.
Alternative names: C5aR2, C5a anaphylatoxin chemotactic receptor 2, C5a anaphylatoxin receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5L2, GPR77 - 基因ID
- 27202
- NCBI登录号
- NM_018485
- UniProt
- Q9P296
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