GPR55 抗体 (Extracellular)
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- 抗原 See all GPR55 抗体
- GPR55 (G Protein-Coupled Receptor 55 (GPR55))
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抗原表位
- AA 160-174, Extracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPR55 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- 原理
- A Rabbit Polyclonal Antibody to GPR55
- 特异性
- 2nd extracellular loop
- 交叉反应 （详细）
- The antibody will not recognize the protein from rat or mouse samples.
- 预测反应
- Human only
- 产品特性
- Anti-Human GPR55 (extracellular) Antibody (ABIN7043163, ABIN7044200 and ABIN7044201)) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot and live cell flow cytometry applications. It has been designed to recognize GPR55 from human samples only.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: Peptide (C)HGKVEKYMSFHNMSD, corresponding to amino acid residues 160-174 of human GPR55
- 亚型
- IgG
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anti-G Protein-Coupled Receptor 55 (GPR55) (AA 261-275), (Extracellular) antibody
GPR55 适用: 小鼠 WB, IHC, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 55 (GPR55) (AA 141-240) antibodyGPR55 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 55 (GPR55) (C-Term) antibodyGPR55 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 55 (GPR55) antibodyGPR55 适用: 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 55 (GPR55) (Cytoplasmic Domain) antibodyGPR55 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 55 (GPR55) (AA 210-319) antibodyGPR55 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 55 (GPR55) (AA 141-240) antibody (AbBy Fluor® 488)GPR55 适用: 人 WB, FACS 宿主: 兔 Polyclonal AbBy Fluor® 488
anti-G Protein-Coupled Receptor 55 (GPR55) (AA 203-222) antibodyGPR55 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 55 (GPR55) (C-Term) antibodyGPR55 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 55 (GPR55) (AA 261-275), (Extracellular) antibody (FITC)GPR55 适用: 小鼠 FACS, LCI 宿主: 兔 Polyclonal FITC
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200-1:1000
- 说明
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Negative Control: BLP-CR061
Blocking Peptide: BLP-CR061
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- GPR55 (G Protein-Coupled Receptor 55 (GPR55))
- 别名
- GPR55 (GPR55 产品)
- 背景
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G-protein coupled receptor 55,GPR55 is an endocannabinoid receptor that belongs to group δ of the rhodopsin-like (class A) receptors. Like all other G-protein coupled receptors, it consists of seven trans-membrane helixes, intracellular C-terminal domain and extracellular N-terminal extension1.The other known cannabinoid receptors, CB1 and CB2 share low homology with GPR55 and have different ligand specificity and different downstream activated cascade. Thus, GPR55 consists on its own a class of cannabinoid receptor2.GPR55 is highly expressed in the striatum and binds a wide range of ligands, among which are endocannabinoids: Anadanine and 2-Arachidonoyl Glycerol, and phytocannabinoids: Tetrahydrocannabinol (THC), abnormal cannabinoid (CBD) and cannabidiol3. Following ligand binding, GPR55 couples to Gα12,13 proteins, which eventually lead to increased intracellular Ca2+ levels2.The endocannabinoid system has a tremendous potential for experimental and clinical research, based on their evolutionary conservation and role in fundamental physiological and pathological processes, including pain modulation, immune function, neuroprotection, cancer, cardiovascular diseases, fertility and appetite4. Clinical studies using cannabinoid receptor agonists and antagonists have suggested their possible use in modulating acute and/or chronic diseases such as hypertension, glaucoma, emesis, anxiety, depression, gastrointestinal and hepatic disorders, ulcerative colitis and neuropathic and inflammatory pain5.
Alternative names: G-protein coupled receptor 55 - 基因ID
- 9290
- NCBI登录号
- NM_005683
- UniProt
- Q9Y2T6
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