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GPR174 抗体 (Extracellular)

GPR174 适用: 人 WB, LCI, IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7043151
发货至: 中国
  • 抗原 See all GPR174 抗体
    GPR174 (G Protein-Coupled Receptor 174 (GPR174))
    抗原表位
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-175, Extracellular
    适用
    • 31
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 31
    克隆类型
    • 31
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    This GPR174 antibody is un-conjugated
    应用范围
    • 21
    • 17
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Live Cell Imaging (LCI), Immunofluorescence (Cultured Cells) (IF (cc))
    原理
    A Rabbit Polyclonal Antibody to GPR174
    特异性
    2nd extracellular loop.
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Human - 15,16 amino acid residues identical, mouse,rat - 13
    产品特性
    Anti-GPR174 (extracellular) Antibody (ABIN7043151, ABIN7044455 and ABIN7044456) is a highly specific antibody directed against an epitope of the human receptor. The antibody can be used in western blot and indirect flow cytometry applications. It has been designed to recognize GPR174 from human, mouse, and rat samples.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174

    亚型
    IgG
    Top Product
    Discover our top product GPR174 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

    Application Dilutions Western blot wb: 1:400

    说明

    Negative Control: (ABIN7235384)

    Blocking Peptide: (ABIN7235384)

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    0.2 mL double distilled water (DDW).
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    GPR174 (G Protein-Coupled Receptor 174 (GPR174))
    别名
    GPR174 (GPR174 产品)
    背景
    G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79,GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.

    Alternative names: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79
    基因ID
    84636
    NCBI登录号
    NM_032553
    UniProt
    Q9BXC1
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