GPR174 抗体 (Extracellular)
Quick Overview for GPR174 抗体 (Extracellular) (ABIN7043151)
抗原
See all GPR174 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 160-175, Extracellular
-
原理
- A Rabbit Polyclonal Antibody to GPR174
-
特异性
- 2nd extracellular loop.
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Human - 15,16 amino acid residues identical, mouse,rat - 13
-
产品特性
- Anti-GPR174 (extracellular) Antibody (ABIN7043151, ABIN7044455 and ABIN7044456) is a highly specific antibody directed against an epitope of the human receptor. The antibody can be used in western blot and indirect flow cytometry applications. It has been designed to recognize GPR174 from human, mouse, and rat samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174
-
亚型
- IgG
-
-
anti-G Protein-Coupled Receptor 174 (GPR174) (AA 291-333) antibody
GPR174 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 174 (GPR174) (Extracellular Domain) antibodyGPR174 适用: 人, 小鼠, 大鼠, 猴, 兔, Cow, 马, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 174 (GPR174) (Extracellular Domain) antibodyGPR174 适用: 人, 猴, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 174 (GPR174) (Cytoplasmic Domain) antibodyGPR174 适用: 人, 猴 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 174 (GPR174) (Internal Region) antibodyGPR174 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 174 (GPR174) (AA 214-263) antibodyGPR174 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 174 (GPR174) (C-Term) antibodyGPR174 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 174 (GPR174) (AA 126-175) antibodyGPR174 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 174 (GPR174) (AA 131-180) antibodyGPR174 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:400
-
说明
-
Negative Control: (ABIN7235384)
Blocking Peptide: (ABIN7235384)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW).
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- GPR174 (G Protein-Coupled Receptor 174 (GPR174))
-
别名
- GPR174
-
背景
-
G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79,GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.
Alternative names: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79 -
基因ID
- 84636
-
NCBI登录号
- NM_032553
-
UniProt
- Q9BXC1
抗原
-
