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GPR174 抗体 (Extracellular Loop)

The 兔 多克隆 anti-GPR174 antibody (ABIN7043151) specifically detects GPR174 in WB, FACS 和 LCI. The antibody is reactive with 人 samples.
产品编号 ABIN7043151
发货至: 中国
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Quick Overview for GPR174 抗体 (Extracellular Loop) (ABIN7043151)

抗原

See all GPR174 抗体
GPR174 (G Protein-Coupled Receptor 174 (GPR174))

适用

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宿主

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克隆类型

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多克隆

标记

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This GPR174 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Live Cell Imaging (LCI)
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    AA 160-175, Extracellular Loop

    原理

    A Rabbit Polyclonal Antibody to GPR174

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Human - 15,16 amino acid residues identical, mouse,rat - 13

    产品特性

    Anti-GPR174 (extracellular) Antibody (ABIN7043151, ABIN7044455 and ABIN7044456) is a highly specific antibody directed against an epitope of the human receptor. The antibody can be used in western blot and indirect flow cytometry applications. It has been designed to recognize GPR174 from human, mouse, and rat samples.

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174

    亚型

    IgG
  • 应用备注

    WB: 1:400

    FC: 5 μg per reaction

    ICC: The optimal concentration should be determined by the user

    IHC: The optimal concentration should be determined by the user

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7235384)

    Blocking Peptide: (ABIN7235384)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

    浓度

    0.8 mg/mL

    缓冲液

    PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    GPR174 (G Protein-Coupled Receptor 174 (GPR174))

    别名

    GPR174

    背景

    Synonyms: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79

    Description: GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.

    基因ID

    84636

    NCBI登录号

    NM_032553

    UniProt

    Q9BXC1
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