GPR174 抗体 (Extracellular Loop)
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Quick Overview for GPR174 抗体 (Extracellular Loop) (ABIN7043151)
抗原
See all GPR174 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-175, Extracellular Loop
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原理
- A Rabbit Polyclonal Antibody to GPR174
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Human - 15,16 amino acid residues identical, mouse,rat - 13
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产品特性
- Anti-GPR174 (extracellular) Antibody (ABIN7043151, ABIN7044455 and ABIN7044456) is a highly specific antibody directed against an epitope of the human receptor. The antibody can be used in western blot and indirect flow cytometry applications. It has been designed to recognize GPR174 from human, mouse, and rat samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174
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亚型
- IgG
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应用备注
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WB: 1:400
FC: 5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235384)
Blocking Peptide: (ABIN7235384)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- GPR174 (G Protein-Coupled Receptor 174 (GPR174))
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别名
- GPR174
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背景
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Synonyms: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79
Description: GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.
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基因ID
- 84636
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NCBI登录号
- NM_032553
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UniProt
- Q9BXC1
抗原
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